Results 71 to 80 of about 8,466,757 (309)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

A scoping review of crowdsourcing and collective intelligence in oral healthcare

open access: yesBMC Oral Health
Objective Diagnostic and treatment errors are detrimental yet relatively common in primary healthcare settings. Crowdsourcing and collective intelligence (CI) in the form of peers’ opinion and group decision-making can lead to modifications in diagnosis ...
Rodrigo J Mariño   +4 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Policy Support and Attitudes towards Refugees: The Roles of Perceived Threat, and Perceived Preferential Treatment by the State

open access: yesPsikoloji Çalışmaları
Research has documented that perceived threats posed by refugees and immigrants shape responses toward these populations in (mostly Western) host societies.
Sevgi Yakın, Nur Soylu Yalçınkaya
doaj   +1 more source

Less well-established forms of knowledge: new positionings in the field of collective mental health

open access: yesSalud Colectiva, 2017
Collective health is a paradigm with a long history in Latin America. Similarly, collective mental health has had an interesting development in certain Latin American countries, even acting to stimulate psychiatric reform.
Angel Martínez-Hernáez   +1 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

National Treatment Purchase Fund annual report 2004.

open access: yes, 2004
The mission of the National Treatment Purchase Fund is to reduce the length of time public patients are on hospital waiting lists by offering them a choice in obtaining access to treatment quickly, safely and to a high standard of patient satisfaction ...
National Treatment Purchase Fund
core  

Collective Dominance Under Scrutiny: Closing the Enforcement Gap or Complicating EU Competition Policy?

open access: yesYearbook of Antitrust and Regulatory Studies
This paper examines the European Commission’s Draft Guidelines on Article 102 TFEU, focusing on their treatment of collective dominance in oligopolistic markets.
Miroslava Marinova
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Áshe: The Force to Make Things Happen

open access: yes, 1990
Newsletter of the Community Artists' Collective in Houston, Texas, discussing news, events, creative works and programs of the Collective, as well as other information and conversations meant to support African-American ...
Community Artists' Collective
core  

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