Results 61 to 70 of about 8,466,757 (309)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Sociologies, 2016 Based on an ethnographic approach, this article describes several challenges that professionals face during the service of collective meals in French nursing homes.
Laura Guérin
doaj
The Treatment of Seed and Seedling Collections
BAUHINIA – Zeitschrift der Basler Botanischen Gesellschaft, 1977 Since 1967, I have been responsible for the correct identification of plants cultivated in the Botanic Garden of the University of Basel. It has become obvious to me that several useful aids to the identification of plants are lacking, namely, a seed and fruit collection and a seedling herbarium covering the life of plants under cultivation in all ...
openaire +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Collective intelligence systems: Classification and modeling
, 2011 Collective intelligence (CI) is an emerging research field that seeks to merge human and machine intelligence, with an aim to achieve results unattainable by either one of these entities alone.
Kapetanios, E +7 more
core +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Entering Norwegian treatment collectives: a study of youths' first impressions and experiences
Scottish Journal of Residential Child Care, 2017 This study focused on the pre-admission and admission phases of residential treatment, assuming that these phases are important for the motivation for treatment and for the kinds of relationships that are established in treatment.
Arvid Lone, Erik Paulsen
doaj +1 more source
Collective behaviors of Drosophila-derived retinal progenitors in controlled microenvironments.
PLoS ONE, 2019 Collective behaviors of retinal progenitor cells (RPCs) are critical to the development of neural networks needed for vision. Signaling cues and pathways governing retinal cell fate, migration, and functional organization are remarkably conserved across ...
Caroline D Pena +4 more
doaj +1 more source