Collectives - Open Access .click

Results 121 to 130 of about 48,438 (304)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero +1 more
wiley +1 more source

Œuvres collectives

, 1993
Œuvres collectives . In: Histoire de l'éducation. n° 59-60, 1993. Numéro spécial : Bibliographie d'histoire de l'éducation française : titres parus au cours de l'année 1990 et suppléments des années antérieures, sous la direction de Isabelle Havelange ...

core +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source

Œuvres collectives

, 1997
Œuvres collectives. In: Histoire de l'éducation. n° 75-76, 1997. Numéro spécial : Bibliographie d'histoire de l'éducation française : titres parus au cours de l'année 1994 et suppléments des années antérieures, sous la direction de Isabelle Havelange. pp.

core +1 more source

Exhibition as School, School as Exhibition Modes of Display and Reception of Educational Platforms Initiated by Artists, Curators and Collectives in Art Institutions

Parse Journal, 2021
Ginevra Ludovici
doaj

Lviv medical community in 1930s: between hope and challenge

, 2019
Materials of International Workshop "Ludwik Fleck and His Thought Collectives" (April 11-14 ...
Hnatiuk, Ola
core

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

Œuvres collectives

, 1996
Œuvres collectives. In: Histoire de l'éducation. n° 71-72, 1996. Numéro spécial : Bibliographie d'histoire de l'éducation française : titres parus au cours de l'année 1993 et suppléments des années antérieures, sous la direction de Isabelle Havelange. pp.

core +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source

cooperation
humans