Results 101 to 110 of about 202,132 (299)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Socio-psychological climate of pedagogical collectives of higher educational institutions and innovative readiness in the conditions of modernization of education

open access: yesВестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2018
The article contains the results of a scientific study on the topical problem of the development of innovative readiness and the socio-psychological climate of pedagogical collectives of higher educational institutions in the context of modernization of ...
Inna B. Avakyan
doaj  

Feminist movements and the construction of comprehensive care strategies for abortion situations in Brazil [PDF]

open access: yesSaúde e Sociedade
This article analyzes the trajectories and strategies developed by Brazilian feminist collectives, Grupo Curumim, Humaniza Coletivo Feminista, and Projeto Vivas, to ensure comprehensive care in abortion-related situations and to overcome the ...
Luanda de Oliveira Lima   +4 more
doaj   +4 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Magnetically actuated sonodynamic nanorobot collectives for potentiated ovarian cancer therapy

open access: yesFrontiers in Bioengineering and Biotechnology
Ovarian cancer presents a substantial challenge due to its high mortality and recurrence rates among gynecological tumors. Existing clinical chemotherapy treatments are notably limited by drug resistance and systemic toxic side effects caused by off ...
Yixuan Zhou   +10 more
doaj   +1 more source

An Introspection: Get the Caravan Moving [PDF]

open access: yes, 2014
The author\u27s reflection about cultural activism and his role and involvement in the Afrikan Hiphop Caravan, in particular the experiences he collected along the road, travelling with the ...
Crenshaw, Mic
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Designing Collectives, Designing Collectivity

open access: yes, 2023
Architecture’s Afterlife interviews have defied any rigid categorization, supporting the argument that the mentioned 38% is not “other than architecture,” or at least not completely. This percentage is understood as practitioners whose work is complementary, even instrumental to architecture.
openaire   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

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