Results 91 to 100 of about 202,132 (299)
Ecology and SocietyCommunity groups are key drivers of ecosystem restoration in many countries. However, there is increasingly recognition that small scale restoration efforts are often insufficient to reverse ongoing biodiversity declines, and questions have been raised ...
Kiely McFarlane +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
L'Ordinaire des Amériques, 2010 Dans le cadre de ma thèse, j’étudie les interactions entre les prostituées et la société dans son ensemble et les diverses représentations collectives de la prostitution qui en découlent.
Marion Giraldou
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
L’utopie pragmatique des collectifs théâtraux des années 2000, ou un hiatus dans l’héritage
Socio-anthropologie, 2016 This paper’s based on the 21st century’s collectives in theatre and on the heritage of the 1960-70’s paradigmatics’experiences. Setted up in the 2000s, the young collectives are mainly pragmatics.
Louise Roux
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Group versus individual approach? A meta-analysis of the effectiveness of interventions to promote physical activity [PDF]
, 2006 The purpose of the study was to conduct a meta-analysis to empirically compare the relative merits of different contexts typically employed in the physical activity intervention literature for five categories of outcomes: adherence, social interaction ...
Burke, Shauna M +4 more
core
Current Opinion in Neurobiology, 2016 In biological function emerges from the interactions of components with only partially aligned interests. An example is the brain-a large aggregation of neurons capable of producing unitary, coherent output. A theory for how such aggregations produce coherent output remains elusive. A first question we might ask is how collective is the behavior of the
Daniels, Bryan C +3 more
openaire +2 more sources