Results 91 to 100 of about 48,438 (304)
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
L’utopie pragmatique des collectifs théâtraux des années 2000, ou un hiatus dans l’héritage
This paper’s based on the 21st century’s collectives in theatre and on the heritage of the 1960-70’s paradigmatics’experiences. Setted up in the 2000s, the young collectives are mainly pragmatics.
Louise Roux
doaj +1 more source
Enquêtes collectives en sciences sociales
Ce colloque organisé par le CESAER et la Maison des sciences de l'Homme de Dijon s’adresse à l’ensemble des chercheurs en sciences humaines et sociales.
core
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The article contains the results of a scientific study on the topical problem of the development of innovative readiness and the socio-psychological climate of pedagogical collectives of higher educational institutions in the context of modernization of ...
Inna B. Avakyan
doaj
Magnetically actuated sonodynamic nanorobot collectives for potentiated ovarian cancer therapy
Ovarian cancer presents a substantial challenge due to its high mortality and recurrence rates among gynecological tumors. Existing clinical chemotherapy treatments are notably limited by drug resistance and systemic toxic side effects caused by off ...
Yixuan Zhou +10 more
doaj +1 more source
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +5 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source

