Results 61 to 70 of about 71,521 (248)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
In the paper, a new syllogistic system is built up. This system simulates a massive-parallel behavior in the propagation of collectives of parasites.
Schumann Andrew, Akimova Ludmila
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
This paper contextualizes my MFA thesis exhibition Honeybee Collectives, exploring the themes of affective interspecies relationships, human community building, expanded cinema, and socially engaged art. Honeybee Collectives is a site-specific multimedia
Veerkamp, Honna M
core +1 more source
Synergism and antagonism in intestinal microbial communities in closed organized collectives
Introduction. The gut microbiota represents the largest part of the entire human microbiome. The formation of a stable microbiota begins at childbirth, continuing to change during life influenced by various exogenous and hereditary factors.
A. V. Ermolaev +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Fuzzy Collectives is a strategically heavy-handed renovation project and a critique of contemporary Chinese cities - cities that are often too large in scale and too singular in program, with few true collective spaces. Fuzzy Collectives reacts to the
Sun, Xiefangzheng
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Dans le cadre de ma thèse, j’étudie les interactions entre les prostituées et la société dans son ensemble et les diverses représentations collectives de la prostitution qui en découlent.
Marion Giraldou
doaj +1 more source

