Results 31 to 40 of about 426 (214)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

New media theory as ontology of the computer code [PDF]

open access: yes, 2006
The work establishes new media studies in relation to different disciplines that were reflecting contemporary technologies in the 20th century. It emphasizes the likeness o f new media theory to posthumanist philosophy.
Kera, Denisa
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Our friendly desert town:Alternative podcast culture in welcome to Night Vale [PDF]

open access: yes, 2018
Despite its frequently horrific context, Night Vale's community aspect represents one of its most-loved facets, with fans embracing and developing the show's fantasy of shared location, listenership, and identity. This chapter posits that Night Vale fans
Hancock, Danielle, Danielle Hancock
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Never alone, except for now: Mediated collectivity in networks [PDF]

open access: yes, 2010
Recent considerations of the relationship between art and technology have assumed that the primary problem art must confront is a world dominated by images, a homogeneous world of spectacle that mediates viewers as mass consumers.
Cohen, Kris
core  

Deconstructing the rock anthem : textual form, participation and collectivity [PDF]

open access: yes
This thesis focuses on the main attributes of rock anthems. It asks the questions, 'What makes a rock anthem?' and 'How may we define a rock anthem?'.
Dockwray, Ruth.
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Fracking Sociality: Architecture, real estate, and the internet’s new urbanism [PDF]

open access: yes, 2020
This chapter explores a set of tendencies that suggest that the internet’s future is linked to a transformation in the technological form of urban real estate. Everything from the spread of sensor-based technology and the impact of technology on property
Moreno, Louis
core   +1 more source

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