Results 41 to 50 of about 426 (214)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Participatory storytelling and the new folklore of the digital age [PDF]

open access: yes, 2013
August 2013School of Humanities, Arts, and Social SciencesDrawing on a century's worth of folklore studies, my examination of variability in digital stories challenges the notion of text as a fixed object of study, and looks at ways that contemporary ...
Newsom, Eric Thomas
core  

The performance of protest [Elektronisk resurs] : Las tesis and the new feminist radicality at the conjunction of digital spaces and the streets [PDF]

open access: yes
In this article, I conduct a multimodal analysis of videos of Las Tesis’ performance “Un Violador En Tu Camino,” posted on YouTube and Twitter, with the aim of obtaining deeper insights into how digital platforms encourage the creation of large-scale ...
Liinason, Mia,, Lund University.
core   +1 more source

The political potential of affective collectivity – exploring Danish fat activism on Instagram [PDF]

open access: yes, 2020
This paper deals with the Danish digital feminist ‘fatosphere’ (Pausé 2015, Lupton 2018, p. 82) and its impact on mainstream media discourses on fatness as a feminist issue.
Christiansen, Lene Bull   +1 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

EKSPRESI KECEMASAN NETIZEN DI MEDIA SOSIAL FACEBOOK TENTANG PANDEMI COVID-19 [PDF]

open access: yes, 2022
Discourse studies and the Covid-19 pandemic have attracted the attention of previous researchers with various topics. However, studies that focus on the anxiety of netizens as expressed through social media Facebook have not been carried out.
Basri, Muhammad Bahly   +2 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Noise to Signal: DIY Music Practice in Melbourne 1976–2016 [PDF]

open access: yes, 2019
This project explores the do-it-yourself (“DIY”) practices of Melbourne experimental and independent music initiatives from the late 1970s until today.
JARED VICTOR DAVIS (5880431)
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy