Results 61 to 70 of about 426 (214)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Developing corporate knowledge management through social media [PDF]

open access: yes, 2008
Tietojohtaminen on organisaation prosessi, joka keskittyy tiedon keräämiseen, organisointiin, analysointiin ja jakamiseen. Yrityksen tietojohtamisen tarkoitus on luoda työympäristö, jossa työntekijät pystyvät kasvattamaan omaa tietouttaan ja käyttämään ...
Säntti, Petra
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The dialogical processes of vernacular mediation: new media and the Karay-a ethnic group of the Philippines. [PDF]

open access: yes, 2013
This thesis examines the extent to which vernacular mediation, or the ongoing, sociohistorically situated, and discursive communicative acts through new media technologies, enables the cultural participation and emancipation of marginal groups.
Umali, Mariane S.A. Medina
core  

Jet quenching for measuring the QCD collectivity temporal structure [PDF]

open access: yes, 2023
In this thesis we use the medium-induced gluon radiation spectrum to study the quark gluon plasma generated at the LHC. In particular, we employ a new computational algorithm that exactly resums the QCD potential without truncations — either in the ...
González Martínez, Marcos
core  

Information and Communication Technologies and Migration [PDF]

open access: yes
Surveying existing literature, this paper starts by identifying links between attainments in human development and the presence of ICTs. The research then looks at instances where ICTs affect the opportunity for migration and how they affect its outcomes.
Hamel, Jean-Yves
core   +4 more sources

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Netball in the lives of New Zealand Women: An Intergenerational Study [PDF]

open access: yes, 2011
This thesis explores the netball experiences of a selection of New Zealand women whom have participated or continue to participate in netball during four distinct historical periods.
Marfell, Amy Elizabeth
core  

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