PVA Nanofibers by Solution Blow Spinning: Processing Principles, Challenges, and Biomedical Applications. [PDF]
Ashraf F, Olmos D, González-Benito J.
europepmc +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Microfabrication Strategies for Silicon Anodes in On-Chip and Miniaturized Batteries. [PDF]
Park H, Lee CS, Bae J.
europepmc +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Selective flotation of chalcopyrite over pyrite in a low-grade copper sulfide ore using selective collectors and non-cyanide depressants. [PDF]
Soltani F +4 more
europepmc +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Barriers and facilitators to research data collection in resource-limited settings: a qualitative study of research coordinators in the Nigeria Implementation Science Alliance Network. [PDF]
Idemili-Aronu N +9 more
europepmc +1 more source

