Results 251 to 260 of about 555,187 (313)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Challenges and needs before implementing routine pulse oximetry within primary care for sick children in West Africa: baseline assessment within the AIRE project. [PDF]

BMJ Glob Health
Hedible KGB, Anago GM, Lenaud S, Neboua D, Zair Z, Sawadogo AG, Louart S, Zombré V, Kaba DF, Sidibe A, Abarry Souleymane H, Busière S, Vignon M, Lamontagne F, Ridde V, Leroy V, AIRE Research Study Group.   +16 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Care management and determinants of day 14 mortality in severely ill children aged under 5 years subsequent to hypoxaemia diagnosed using routine pulse oximetry in primary care: evidence from the AIRE project. [PDF]

BMJ Glob Health
Hedible KGB, Sawadogo AG, Zair Z, Kargougou DG, Méda B, Peters Bokol L, Kolié JS, Louart S, Ouédraogo Yugbaré S, Diakite AA, Diallo IS, Abarry Souleymane H, Busière S, Lamontagne F, Shepherd S, Ridde V, Leroy V, AIRE Research Study Group.   +17 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Understanding health innovation adoption: a realist evaluation of pulse oximeter implementation in primary care for children under 5 in four West African countries. [PDF]

BMJ Glob Health
Louart S, Balde H, Coulibaly A, Dagobi AE, Kadio K, Hedible KGB, Leroy V, Robert E, Ridde V, AIRE study group.   +9 more
europepmc   +1 more source

Study on Collectors Committee of Collectors (1)

FLOTATION, 1955
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Environmental and energetic exergetic sustainability of stevia leaf drying in a PVT indirect solar dryer with variable airflow and tray levels. [PDF]

Sci Rep
Elwakeel AE, Oraiath AAT, Tantawy A, Székács A, Saeed O, Eid MH, Mahmoud SF, Aljumayi H, AlQthanin RN, Abdallah SE, Yousif IAH, Tantawy AA.   +11 more
europepmc   +1 more source