Results 111 to 120 of about 74,897 (302)

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Lethbridge Collegiate Institute Spotlite 1955

open access: yes, 2016
The annual publication of the students of Lethbridge Collegiate Institute, Lethbridge, Alberta.(1954-55)pdf"Youth is not entirely a time of life—it is a state of mind . . . Nobody grows old by merely living a number of years.
Lethbridge Collegiate Institute
core  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Lethbridge Collegiate Institute Spotlite 1949

open access: yes, 2016
The annual publication of the students of Lethbridge Collegiate Institute, Lethbridge, Alberta.(1948-49)pdfTHE SPOTLITE PRO SCOLA ET PRO PATRIA ENROLMENT - 600 STUDENTS Published by The Student Body of the Lethbridge Collegiate Institute Lethbridge ...
Lethbridge Collegiate Institute
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Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Economic Impact of Collegiate Bass Tournaments: Experiences from Auburn University [PDF]

open access: yes
Recreation and tourism associated with collegiate bass tournaments can play a major role in local economic development as the dollars anglers and tournament organizers spend work their way through the economy.
Swaim, Jenny, Myles, Albert E.
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Lethbridge Collegiate Institute Yearbook 2009

open access: yes, 2020
The annual publication of the students of Lethbridge Collegiate Institute, Lethbridge, Alberta.(2008-09)pdfINDIVIDUAL t 2009 Lethbridge Collegiate Institute 1701 5th Avenue South Lethbridge, AB, T1J0W4 Url: http://moodle.lethsd.ab.ca/lciweb ...
Lethbridge Collegiate Institute
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Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Lethbridge Collegiate Institute Spotlite 1960

open access: yes, 2016
The annual publication of the students of Lethbridge Collegiate Institute, Lethbridge, Alberta.(1950-60)pdf"Owls have acquired an unearned reputation for wisdom simply because they look profound all the time and hoot only occasionally” — Niti Sastras ...
Lethbridge Collegiate Institute
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