Results 131 to 140 of about 74,897 (302)

Northeast Wisconsin Collegiate Brass Choir [PDF]

open access: yes, 2016
The Northeastern Wisconsin Collegiate Brass Choir is an all-faculty ensemble comprised of members from St. Norbert College, Lawrence University, Ripon College, UW Green Bay, UW Oshkosh and UW Stevens Point.
Northeastern Wisconsin Collegiate Brass Choir
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Lethbridge Collegiate Institute Spotlite Reunion 1971-1974

open access: yes, 2016
Dedicated to the students who attended the Lethbridge Collegiate Institute during the years of 1971 - 1974, Lethbridge, Alberta.(1987)pdfDedicated to tfie students who attended the Lethhvidqe Codeqiate Institute during tfie years of 1971 - 1974 Reunion ...
Lethbridge Collegiate Institute
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Lethbridge Collegiate Institute Yearbook 2006

open access: yes, 2016
The annual publication of the students of Lethbridge Collegiate Institute, Lethbridge, Alberta.(2005-06)pdfLethbridge Collegiate Institute 1701 5th Avenue South Lethbridge, AB, T1J0W4 http://lsdwcb.lethsd.ab.ca/LCI/home Student Enrollment - 1567 ...
Lethbridge Collegiate Institute
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Collegiate Singers, University Chorale, November 11, 1979

open access: yes, 2018
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, November 11, 1979, program no. 82 of the Department of Music's 1979-1980 season.1st work: Collegiate Singers ; University Chorale ; Bernard Floyd ...
Collegiate Singers (Western Michigan University)
core   +2 more sources

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

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