Results 71 to 80 of about 359,595 (336)

LCD ROOT Simulation and Analysis Tools [PDF]

open access: yes, 2001
The North American Linear Collider Detector group has developed a simulation program package based on the ROOT system. The package consists of Fast simulation, the reconstruction of the Full simulated data, and physics analysis utilities.Comment: 5 pages
Abe, Toshinori, Iwasaki, Masako
core   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Optimization of Cation Exchange for the Separation of Actinium-225 from Radioactive Thorium, Radium-223 and Other Metals

open access: yesMolecules, 2019
Actinium-225 (225Ac) can be produced with a linear accelerator by proton irradiation of a thorium (Th) target, but the Th also underdoes fission and produces 400 other radioisotopes.
Jonathan Fitzsimmons   +6 more
doaj   +1 more source

Anatomy of inclusive tt‾W production at hadron colliders

open access: yesPhysics Letters B, 2020
In LHC searches for new and rare phenomena the top-associated channel pp→tt‾W±+X is a challenging background that multilepton analyses must overcome. Motivated by sustained measurements of enhanced rates of same-sign and multi-lepton final states, we ...
Stefan von Buddenbrock   +2 more
doaj   +1 more source

Collider scope: when selection bias can substantially influence observed associations

open access: yesbioRxiv, 2016
Large-scale cross-sectional and cohort studies have transformed our understanding of the genetic and environmental determinants of health outcomes. However, the representativeness of these samples may be limited – either through selection into studies ...
M. Munafo   +4 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

Science Requirements and Detector Concepts for the Electron-Ion Collider [PDF]

open access: yesNuclear Physics, 2021
R. A. Khalek   +413 more
semanticscholar   +1 more source

Luminosity monitors at the LHC [PDF]

open access: yes, 2000
We study the theoretical accuracy of various methods that have been proposed to measure the luminosity of the LHC pp collider, as well as for Run II of the Tevatron p barp collider.
Khoze, V. A.   +3 more
core   +3 more sources

Protein Tyrosine Phosphatase 4A1 (PTP4A1) Regulates Early Events in Colorectal Cancer Intraperitoneal Dissemination in the Aged Male Host

open access: yesAging and Cancer, EarlyView.
Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang   +17 more
wiley   +1 more source

Review of IoT Systems for Air Quality Measurements Based on LTE/4G and LoRa Communications

open access: yesIoT
The issue of air pollution has recently come to light due to rapid urbanization and population growth globally. Due to its impact on human health, such as causing lung and heart diseases, air quality monitoring is one of the main concerns.
Mpho Gift Doctor Gololo   +9 more
doaj   +1 more source

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