Results 251 to 260 of about 1,678,458 (327)

Roundabout Mechanism of Ion-Molecule Nucleophilic Substitution Reactions. [PDF]

open access: yesACS Phys Chem Au
Wu X   +5 more
europepmc   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto   +2 more
wiley   +1 more source

Probing Early α‐Synuclein Oligomers: Insights Into Aggregation Pathways of NACore and preNAC Segments Probed by Trapped Ion‐Mobility Mass Spectrometry and Fluorescence Spectroscopy

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Misfolding and aggregation of α‐Synuclein (α‐Syn) play a central role in Parkinson's disease (PD), with oligomeric intermediates implicated as key toxic species. Here, we investigate the aggregation of two α‐Syn segments, the NACore (68GAVVTGVTAVA78, WT‐PD1) and the preNAC region (47GVVHGVATVA56, WT‐PD2), using high‐resolution trapped ion ...
Agathe Depraz Depland   +3 more
wiley   +1 more source

Underwater Plasma‐Driven Decomposition of Tetramethylammonium Hydroxide (TMAH) Under Different Applied Field Strengths

open access: yesPlasma Processes and Polymers, EarlyView.
Underwater plasma efficiently degrades TMAH via in situ generation of reactive oxygen and nitrogen species. An underwater plasma accelerates mass transfer and radical attack on the quaternary ammonium cation. Time‐resolved analyses show decreasing TOC and conversion of organic carbon toward inorganic species, with concomitant formation of NO3–/NH4+ at ...
Ki‐Taik Lee   +4 more
wiley   +1 more source

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