Results 71 to 80 of about 279,849 (339)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Dynamic Analysis of Monopile-Type Offshore Wind Turbine Under Sea Ice Coupling With Fluid-Structure Interaction

Frontiers in Marine Science, 2022
The interaction between vertical offshore wind turbine (OWT) and sea ice with fluid is a complex process including local and global crushing of ice fragments and vibration of OWT.
Yingzhou Liu, Yingzhou Liu, Wei Shi, Wei Shi, Wenhua Wang, Wenhua Wang, Xin Li, Xin Li, Shengwenjun Qi, Shengwenjun Qi, Bin Wang   +10 more
doaj   +1 more source

Rethinking Tag Collisions for Replay and Relay Attack Resistance in Backscatter Networks [PDF]

, 2023
Hoorin Park, Wonjun Lee
openalex   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Floquet theory of microwave absorption by an impurity in two dimensional electron gas

, 2017
We investigate the dynamics of a two-dimensional electron gas (2DEG) under circular polarized microwave radiation in presence of dilute localized impurities.
Chepelianskii, A. D., Shepelyansky, D. L.   +1 more
core   +2 more sources

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Research on Collision Restitution Coefficient Based on the Kinetic Energy Distribution Model of the Rocking Rigid Body within the System of Mass Points

Buildings
Rocking structures exhibit significant collapse resistance during earthquakes. In studies of rocking rigid bodies, the collision restitution coefficient is typically determined based on the classical model of the rocking rigid bodies. However, during the
Qiuyu Mao, Tongfa Deng, Botan Shen, Yuexin Wang   +3 more
doaj   +1 more source

On the failure behaviour to striking bow penetration of impacted marine-steel structures

Curved and Layered Structures, 2018
Demands for water transportation modes are continuously increasing as rapid economic and industrial growths in the recent decade. Ship as representative of the water transportation is generally needed to carry various products from one location to ...
Prabowo Aditya Rio, Muttaqie Teguh, Sohn Jung Min, Bae Dong Myung, Setiyawan Agus   +4 more
doaj   +1 more source

An efficient multi-use multi-secret sharing scheme based on hash function [PDF]

Applied Mathematics Letters, 23 (2010), 2011
In this paper, a renewable, multi-use, multi-secret sharing scheme for general access structure based on one-way collision resistant hash function is presented in which each participant has to carry only one share. By applying collision-resistant one-way hash function, the proposed scheme is secure against conspiracy attacks even if the pseudo-secret ...
arxiv   +1 more source