Results 51 to 60 of about 99 (99)
Substrate Engineering for Durable Omniphobic Liquid‐Like Surfaces
Advanced Functional Materials, EarlyView.The significant yet less investigated role of substrates in determining the liquid‐repellency and mechanical durability of liquid‐like surfaces (LLSs) is explored. Thick and crack‐free sol–gel silica intermediary layers are developed that can smoothen substrate asperity roughness even at the micron scale, enabling omniphobic polydimethylsiloxane‐based ...
Tao Wen +6 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Ambient‐dried composite aerogels integrating MOF‐303, TEMPO‐oxidized cellulose nanofibers (TOCNF), and hygroscopic salts enable high‐performance atmospheric water harvesting (AWH), achieving competitive uptake at both low and high humidity. Enhanced with a solar‐evaporation layer, these scalable aerogels support self‐sustained plant growth in a ...
Ahmadreza Ghaffarkhah +12 more
wiley +1 more source
Advanced Functional Materials, EarlyView.The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar +6 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A novel solid polymer electrolyte (SPE) to overcome interface instability in high‐energy‐density lithium metal batteries has been developed. By enhancing ionic conductivity, mechanical elasticity, and adhesion strength through all‐material UV‐crosslinking, the SPE ensures uniform lithium‐ion flow and stable performance—even after bending or cutting ...
Sung Yeon Bae +7 more
wiley +1 more source
Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim +9 more
wiley +1 more source
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo +11 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto +2 more
wiley +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Small extracellular vesicles (sEVs) are encapsulated into protective shells composed of metal‐phenolic networks (MPNs) and secondary poly(ethylene glycol) layers. This surface modification approach enhances the storage stability of sEVs while maintaining their integrity and functionality. The shells can be selectively disassembled under mild conditions.
Chenyu Wang +8 more
wiley +1 more source
Light‐Activatable Hyaluronic Acid‐Derivatives Releasing Nitric Oxide and Their Delivery in the Skin
Advanced Healthcare Materials, EarlyView.This work explores the development of photoactivatable hyaluronic acid (HA) derivatives functionalized with nitric oxide (NO) photodonors for light‐controlled therapeutic applications. The HA derivatives demonstrate enhanced keratinocyte proliferation and migration, effective NO release, and skin penetration when formulated as microemulsions.
Giuseppe Longobardi +7 more
wiley +1 more source