Results 91 to 100 of about 37,793 (228)

Length of the Adult Human Colon in Health and Constipation Measured Using Magnetic Resonance Imaging

open access: yesNeurogastroenterology &Motility, EarlyView.
Colon length was measured in adult healthy volunteers, people with chronic constipation, and people with IBS with constipation using MRI. Colon length is significantly longer in chronic constipation. The chronically constipated colon is unable to accommodate longitudinally in response to fluid influx from a macrogol challenge.
Faiz Alqarni   +16 more
wiley   +1 more source

Effect of Linaclotide on Colonic Motility Assessed With Intraluminal Colonic High‐Resolution Manometry in Healthy Subjects. An Acute, Open Label, Randomized, Crossover, Reader‐Blinded Study

open access: yesNeurogastroenterology &Motility, EarlyView.
Our study showed that, in healthy controls, acute administration of linaclotide increased the total number of long‐distance propagating and the pre‐prandial pancolonic pressurizations. Further studies need to address whether the observed effects are directly or indirectly mediated by the mechanism of action of this useful medication to treat chronic ...
Christian Lambiase   +7 more
wiley   +1 more source

GENDER FEATURES OF THE STRUCTURE OF COLON EPITHELIAL NEOPLASMS

open access: yesМедицина в Кузбассе
The aim of the research – the article is devoted to the evaluation of the structure of epithelial neoplasms in different parts of the colon due to the gender of the patient. Materials and methods.
Алексей Григорьевич Короткевич   +1 more
doaj  

Hypertrophy of the neurons in the ileum of rats infected with cysts of Toxoplasma gondii (genotype II) = Hipertrofia de neurônios do íleo de ratos infectados com cistos de Toxoplasma gondii (genótipo II)

open access: yesActa Scientiarum: Biological Sciences, 2009
This paper verified possible alterations caused by a genotype II Toxoplasma gondii strain with respect to the total number and morphometry of the myenteric neurons in the terminal ileum and descending colon of rats.
Elaine Yae Yamashita Sugauara   +4 more
doaj  

Population genomic signatures of founding events in autonomously self‐fertilizing plants: a test with Impatiens capensis

open access: yesNew Phytologist, EarlyView.
Summary Autonomously self‐fertilizing plants possess disproportionate abilities to found populations. Viewed from the metapopulation perspective, founding events should be frequent in such plants, but the intensity and timing of bottlenecks and recovery should vary among populations.
Daniel J. Schoen, Rachel H. Toczydlowski
wiley   +1 more source

CD36 and Its Role in Obesity

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity is understood as a condition driven by interactions between genetics and environmental factors. The role of CD36 in the regulation of lipid metabolism and ectopic fat accumulation emerges as a key area of interest. This review presents CD36 not only as a crucial facilitator of fatty acid uptake but also as a regulator of how and where ...
Nahuel Garcia   +5 more
wiley   +1 more source

Laws and Reasons Why

open access: yesAnalytic Philosophy, EarlyView.
ABSTRACT Laws play some role in explanations: at the very least, they somehow connect what is explained, or the explanandum, to what explains, or the explanans. Thus, thermodynamical laws connect the match's being struck and its lightning, so that the former causes the latter; and laws about set formation connect Socrates' existence with {Socrates}'s ...
Julio De Rizzo
wiley   +1 more source

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

open access: yesExperimental Physiology, EarlyView.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh   +6 more
wiley   +1 more source

GABAB receptor‐mediated modulation of sensory neuron excitability: Roles of CaV2.2, G‐protein‐coupled inwardly rectifying potassium (GIRK) channels, and hyperpolarisation‐activated cyclic nucleotide‐gated (HCN) channels in human and mouse nociception

open access: yesExperimental Physiology, EarlyView.
Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela   +4 more
wiley   +1 more source

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