Results 91 to 100 of about 41,603 (297)

Aberrant alternative splicing of purinergic receptor P2RX4 prevents sensitivity towards combinatorial treatment in colorectal and pancreatic cancer

The Journal of Pathology, EarlyView.
Abstract Recently, we suggested the combination of chemotherapy and P2RX4 inhibition as a promising novel therapeutic approach for P2RX4‐expressing epithelial tumors to prevent paracrine resistance. Here, we aimed to assess whether determining P2RX4 expression status in colorectal and pancreatic cancer patients would allow stratification of potentially
Christoph Steup, Julian Dosch, Christopher Dietz‐Fricke, Sara Khosraviseftejani, Esther Engel, Adalbert F de Valk, Dominic Menger, Patrick Welker, Peter J Wild, Kilian B Kennel, Maja Kantlehner, Paul K Ziegler, Florian R Greten   +12 more
wiley   +1 more source

An unusual cause of acute lower gastrointestinal bleeding: lung adenocarcinoma metastasis to the descending colon

Clinical Case Reports, 2017
Key Clinical Message Lung adenocarcinoma with symptomatic GI metastasis occurs seldom in everyday clinical practice. However, as diagnostic modalities, therapeutic interventions, and supportive care for cancer evolve, it is likely that the clinician ...
Ioannis S. Papanikolaou, Paraskevas Gkolfakis, Georgios Tziatzios, Konstantinos Grammatikos, Ioannis G. Panayiotides, Zoi Tsakiraki, Irina Zinovieva, George D. Dimitriadis, Konstantinos Triantafyllou   +8 more
doaj   +1 more source

Mesenteric Panniculitis: An Enigma [PDF]

Iranian Journal of Medical Sciences
Mesenteric panniculitis (MP) is one of the few rare chronic inflammatory disorders with an unknown etiology.
Amit Kumar Gupta, Niraj Shrivastava
doaj   +1 more source

Accelerating the prioritisation of plant species with underexplored medicinal potential: The pm4mp (Phylogenetic Methods for Medicinal Plants) R package

PLANTS, PEOPLE, PLANET, EarlyView.
Medicinal plants used in ethnobotanical traditions to treat or prevent diseases have gained renewed interest for their largely untapped potential in drug discovery. In this study, we developed and tested novel methods to prioritise plant species based on their unexplored medicinal potential. By enabling researchers to target the most promising species,
Giovanni Zecca, Elisa Toini, Massimo Labra, Fabrizio Grassi   +3 more
wiley   +1 more source

An Uncommon Presentation in Behçet’s Disease: Recovered Descending-Colon Perforation with Conservative Medical Therapy: Case Report

, 2011
ABS TRACT Behçet’s disease is a multisystem disorder. Intestinal involvement is common in patients from the Far East, but is rare among those from the Middle East. The most frequent area of involvement is the ileocecal region.
Işık, Burak, Murat ALADAĞ, Yüksel SEÇKİN, Yağmur, Murat, Aladağ, Murat, Burak IŞIK, Ulvi DEMİREL, Harputoğlu, Muhsin Murat Muhip, Murat YAĞMUR, Murat MM HARPUTLUOĞLU, Seçkin, Yüksel, Demirel, Ulvi   +11 more
core   +1 more source

Factors affecting the removal of grass seed foreign bodies in canine patients

Veterinary Record, EarlyView.
Abstract Background Migrating grass seed foreign bodies (GSFBs) commonly cause pathology in canine patients. Anecdotally, antibiotic treatment eliminates the fluid pockets that usually form around GSFBs, complicating identification and retrieval. Methods Radiology reports tagged with ‘soft tissue foreign body’ were retrospectively analysed to identify ...
Charli M. Twyford, Conor Rowan
wiley   +1 more source

Laparoscopic surgery for colorectal cancer with persistent descending mesocolon

World Journal of Surgical Oncology, 2019
Background Persistent descending mesocolon (PDM) is caused by the absence of fusion of the descending colon to the retroperitoneum. We herein report two colorectal cancer cases with PDM that were treated with laparoscopic surgery.
Yukiharu Hiyoshi, Yuji Miyamoto, Kojiro Eto, Yohei Nagai, Masaaki Iwatsuki, Shiro Iwagami, Yoshifumi Baba, Naoya Yoshida, Hideo Baba   +8 more
doaj   +1 more source

Matrices for site-specific controlled-delivery of 5-fluorouracil to descending colon

, 2005
Colon-specific controlled-delivery 5-fluorouracil (5-FU) matrices for the treatment of colorectal carcinoma were prepared and evaluated. Matrices are destined to be introduced into enteric-coated capsules and thereby carried to and liberated in the ileum.
ZAMBITO, YLENIA, SERAFINI, MARIA FRANCESCA, DI COLO, GIACOMO, A. BAGGIANI, CARELLI, VERA   +4 more
core   +1 more source

Potentially Preventable Mortality After Elective Colorectal Cancer Surgery: Insights From a National Surgical Mortality Audit

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Colorectal cancer (CRC) is a significant contributor to preventable deaths worldwide. The assessment of potentially avoidable mortality following elective CRC surgery has yet to be reported. The Australian and New Zealand Audit of Surgical Mortality (ANZASM) seeks to peer‐review all deaths associated with surgical care.
Sergei Bedrikovetski, Luke Traeger, Nathan Procter, Helena S. Kopunic, Guy J. Maddern   +4 more
wiley   +1 more source

Use of Laxative-Augmented Contrast Medium Increases the Accuracy in the Detection of Colorectal Neoplasms

Diagnostics
Colonic adenomas are considered a precursor of colorectal cancer. A 75-year-old woman had a history of post-operation left breast cancer. She received an excision when the left chest wall recurred.
Li-Yu Chen, Jong-Dar Chen, Yen-Kung Chen
doaj   +1 more source