Results 101 to 110 of about 49,238 (225)
The Journal of Pathology, Volume 270, Issue 1, Page 55-68, September 2026.Abstract Recently, we suggested the combination of chemotherapy and P2RX4 inhibition as a promising novel therapeutic approach for P2RX4‐expressing epithelial tumors to prevent paracrine resistance. Here, we aimed to assess whether determining P2RX4 expression status in colorectal and pancreatic cancer patients would allow stratification of potentially
Christoph Steup +12 more
wiley +1 more source
Protein Science, Volume 35, Issue 9, September 2026.Abstract Disulfide‐rich miniproteins constitute compact and highly stable scaffolds of growing interest for molecular and structural engineering. Schistosomins are ~80‐residue proteins conserved across gastropods that form a long‐standing orphan family whose structure and biological roles have remained unknown.
Oleg Melnyk +13 more
wiley +1 more source
Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang +4 more
wiley +1 more source
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 9, Page 1860-1870, September 2026.Seromucinous borderline ovarian tumors frequently appear as unilateral, left‐sided cysts with ground‐glass echogenicity and moderately vascularized solid components. Their strong association with ipsilateral endometriosis provides crucial sonographic and clinical clues for an accurate preoperative diagnosis.
Simona Del Forno +10 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 15, 15 August 2026.Using an interpretable deep learning framework (CARSS) applied to multi‐tissue single‐cell RNA sequencing, we identify CD34⁺PDGFRα⁺ telocytes (CPTCs) as the primary mechanosensors bridging somatic acupuncture stimulation and visceral repair. Mechanical force at acupoints activates an AP‐1/Hsp70 immediate‐early gene program in fascial CPTCs, triggering ...
Haixiang Huang +12 more
wiley +1 more source
Direct observation of an exposed blood vessel in a colonic diverticulum using ultrathin endoscopy
DEN OpenIn recent years, cases of diverticular bleeding have become more common. Although identifying the bleeding diverticulum is difficult, it is even more difficult to identify the exposed blood vessels in the bleeding diverticulum.
Kensuke Suzuki +2 more
doaj +1 more source
Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.Abstract Background The current standard radiotherapy treatment planning workflow typically requires several hours to days, during which patients must wait before treatment can be initiated. In certain oncological situations, however, treatment should commence as soon as possible.
Robert Schindhelm +14 more
wiley +1 more source
ACR Open Rheumatology, Volume 8, Issue 8, August 2026.Objective Our objective was to identify and describe the clinical characteristics and outcomes in patients with pre‐existing idiopathic inflammatory myopathies (IIMs) in the Veterans Health Administration (VHA) treated with immune checkpoint inhibitors (ICIs). Methods All veterans receiving ICI infusions were identified.
Denis Krutko +8 more
wiley +1 more source
Severe Ulcerative Colitis With Cytomegalovirus Colitis Treated by Early Surgery: A Case Report
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Acute severe ulcerative colitis complicated by cytomegalovirus infection requires individualized management, and timely surgical intervention should be considered in carefully selected high‐risk patients who are unlikely to benefit from further medical therapy.
Hiroyuki Fujimura +4 more
wiley +1 more source