Results 111 to 120 of about 49,238 (225)
ABSTRACT The third reported case of synchronous colorectal adenocarcinoma and EBV‐positive DLBCL in an 87‐year‐old patient confirms the rarity of this synchronous tumor. Despite segmental resection, the patient died from postoperative complications, highlighting the need for multidisciplinary research into pathogenesis and management.
Fen Liu +3 more
wiley +1 more source
SLC7A5‒Kyn/XANA signalling activates AhR to drive EMT and metastatsis. SLC7A5 knockdown enhances macrophage antigen presentation and reverses CD8+ T‐cell exhaustion. SLC7A5 knockdown induces antigen‐driven and IgG‐secreting B‐cell clonal expansion. Combination of SLC7A5 inhibition and anti‐PD‐1 therapy offers clinical targeting.
Yaohao Luo +8 more
wiley +1 more source
Level of Vascular Ligation for Sigmoid Colon Cancer: Does It Matter? The Pina Low‐T Study
ABSTRACT Background and Methods In sigmoid colon cancer surgery, the inferior mesenteric artery (IMA) can be ligated at its origin (high ligation, HLG) or distal to the left colic artery bifurcation (low ligation, LLG). While high ligation facilitates lymph node harvest and mobilization, it may compromise colonic perfusion and increase nerve injury ...
Silvia Picotto +7 more
wiley +1 more source
Uptake and Transport of Monotropein and Monotropein Esters in a Caco‐2/HT29‐MTX‐E12 Co‐Culture Model
Monotropein and its naturally occurring ester derivatives (monotropein‐10‐coumarate and monotropein‐10‐cinnamate) from Gaultheria spp. berries exhibit limited intestinal permeability in a validated Caco‐2:HT29‐MTX‐E12 co‐culture model. Absorption occurs predominantly via passive diffusion, with partial SGLT1‐ and OATP‐mediated uptake contribution for ...
Christian Zielinski +7 more
wiley +1 more source
Ultrasmall Cyclodextrin‐Based Nanogels as Drug Delivery Systems
Cyclodextrin (CD) nanogels provide a highly effective, biocompatible platform for advanced drug delivery. These specialized networks successfully encapsulate active ingredients, significantly improving overall drug solubility. Furthermore, the resulting nanogels exhibit enhanced toxicity toward cancer cell lines compared to the parent CDs.
Andrea Cesari +7 more
wiley +1 more source
ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models.
Anders Peder Højer Karlsen +15 more
wiley +1 more source
Curative Surgery for Malignant Sigmoid-Duodenal Fistula Caused by Colon Cancer: A Case Report. [PDF]
Aso S +8 more
europepmc +1 more source
Phenotypic Expansion and Molecular Implications in Recessive FUZ ‐Related Ciliopathy
Our patient with homozygous FUZ p.Arg234Trp, potentially altering FUZ‐CPLANE2 interactions, presented with aorto‐pulmonary window, Hirschsprung disease, and shared phenotypes with previously reported ciliopathy patients. This report provides additional evidence for FUZ as a causative gene for ciliopathy, offering novel insights into the phenotype ...
Yosuke Ogawa +4 more
wiley +1 more source
Diagnostic Value of Spectral CT-Derived Extracellular Volume Fraction in the Early Detection of Sigmoid Colon Metastasis from Bladder Cancer: A Case Report. [PDF]
Peng M +5 more
europepmc +1 more source

