Results 211 to 220 of about 207,764 (268)
AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint
Advanced Science, EarlyView.AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz +4 more
wiley +1 more source
Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
Advanced Science, EarlyView.In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source
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2000
Preface Introduction ASIAN MEMORIES Dolores ROMERO LOPEZ: Redirections in Orientalism Daisuke NISHIHARA: China As Japan's Orient Kazue NAKAMURA: Colonizer Colonized Dorothy WONG: 'Domination by Consent' Thomas Y.T. LUK: Post-colonialism and Contemporary Hong Kong Theatre Kwok-kan TAM: Identity on the Bridge Bernadette REY-MIMOSO RUIZ: Visages ...
Theo D'haen, Patricia Krüs
openaire +1 more source
Preface Introduction ASIAN MEMORIES Dolores ROMERO LOPEZ: Redirections in Orientalism Daisuke NISHIHARA: China As Japan's Orient Kazue NAKAMURA: Colonizer Colonized Dorothy WONG: 'Domination by Consent' Thomas Y.T. LUK: Post-colonialism and Contemporary Hong Kong Theatre Kwok-kan TAM: Identity on the Bridge Bernadette REY-MIMOSO RUIZ: Visages ...
Theo D'haen, Patricia Krüs
openaire +1 more source
Radiology, 1979
Angiodysplasia of the colon was diagnosed by arteriography in 33 patients. Approximately one fourth of the lesions were located in the left side of the colon. Three patients with sigmoid lesions had a second lesion elsewhere in the gastrointestinal tract. The lesions on the left involved a more extensive segment of bowel than those on the right. Almost
Miller, K.D. +3 more
openaire +3 more sources
Angiodysplasia of the colon was diagnosed by arteriography in 33 patients. Approximately one fourth of the lesions were located in the left side of the colon. Three patients with sigmoid lesions had a second lesion elsewhere in the gastrointestinal tract. The lesions on the left involved a more extensive segment of bowel than those on the right. Almost
Miller, K.D. +3 more
openaire +3 more sources
Medical Hypotheses, 2000
Epidemiological findings on the relation between foods and colon cancer are inconsistent. Many, but far from all, found positive associations for meat and fat and negative ones for vegetables and fruits. Explanations so far have focused on direct biochemical conversions in the colon or transit time, but they remain unable to explain the contradictory ...
openaire +2 more sources
Epidemiological findings on the relation between foods and colon cancer are inconsistent. Many, but far from all, found positive associations for meat and fat and negative ones for vegetables and fruits. Explanations so far have focused on direct biochemical conversions in the colon or transit time, but they remain unable to explain the contradictory ...
openaire +2 more sources
The Colonic Microbiota and Colonic Disease
Current Gastroenterology Reports, 2012The colonic ecosystem differs from that in the proximal gut in several important respects. The colonic microbiota represents the largest population of microbes colonizing humans from birth. Constraints on bacterial numbers, composition, and interaction with the host involve not only the innate and acquired immune system, but also the colonic mucin ...
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THE ALTERED COLON IN COLONIC OBSTRUCTION
American Journal of Roentgenology, 1972A review of 110 cases of colonic obstruction due to carcinoma demonstrated a variety of alterations in the distended colon on the plain roentgenograms. These findings were: predominantly fluid-filled distention; mottled fluid; accentuation of haustrations in localized areas; decreased haustrations; thickened septa; irregular septa; increased numbers of
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Canadian Review of American Studies, 1988
Nicholas Canny and Anthony Pagden, eds. Colonial Identity in the Atlantic World, 1500-1800. Princeton: Princeton University Press, 1987. xi + 290 pp. Colonial identity is, apparently, an inherently good thing. The search for it is not so much a field as an academic agribusiness.
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Nicholas Canny and Anthony Pagden, eds. Colonial Identity in the Atlantic World, 1500-1800. Princeton: Princeton University Press, 1987. xi + 290 pp. Colonial identity is, apparently, an inherently good thing. The search for it is not so much a field as an academic agribusiness.
openaire +1 more source