Results 291 to 300 of about 1,581,828 (334)

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

Advanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou, Cheng‐Wei Ju, Nicholas A. Egan, Yanjun Wei, Yunfei Wang, Minghao Dang, Tianyi Zhou, Leilei Shi, Ningbo Zheng, Si Chen, Ashley M. Guerrero, Xiaofang Liang, Wanfu Wu, Areej Akhtar, Chitra Dhiman, Debanwita Roy Burman, Andro E. Gerges, Mason D. Flores, Han Li, Li‐Sheng Zhang, Marleen Kok, Xiaobo Mao, Linghua Wang, Qin Feng, Yiwen Chen, Sanghoon Lee, Daniel J. McGrail, Nidhi Sahni, Chuan He, Amir A. Jazaeri, Weiyi Peng   +30 more
wiley   +1 more source

Case Report: Endoscopic submucosal dissection and endoscopic transcecal appendectomy for synchronous sigmoid and appendiceal adenomas with calcified Schistosoma eggs. [PDF]

Front Oncol
Zhou Y, Zhu L, Niu D, Xu L, Xu X, Kang X, Du Y, He D.   +7 more
europepmc   +1 more source

ggalign: Bridging the Grammar of Graphics and Biological Multilayered Complexity

Advanced Science, EarlyView.
The ggalign package provides a comprehensive framework for composable visualization built on top of ggplot2. Its primary purpose is to enable the construction of complex multi‐plot layouts with consistent observation alignment across plots, particularly for high‐dimensional data contexts such as genomics, transcriptomics, and microbiome studies ...
Yun Peng, Shan Jiang, Yuxuan Song, Peng Luo, Jianfeng Li, Dehua Hu, Jian‐Guo Zhou, Guangchuang Yu, Tao Xu, Shixiang Wang   +9 more
wiley   +1 more source

Artificial intelligence-assisted versus conventional reading in pan-intestinal capsule endoscopy for suspected mid-lower gastrointestinal bleeding: a retrospective analysis of a prospective cohort. [PDF]

BMJ Open Gastroenterol
Rosa B, Mascarenhas Saraiva MJ, Afonso J, Cúrdia Gonçalves T, Mendes F, Moreira MJ, Martins M, Dias de Castro F, Ribeiro T, Cardoso P, Almeida MJ, Mota J, Ferreira J, Macedo G, Cotter J.   +14 more
europepmc   +1 more source

Engineering Bacteria as Living Therapeutics in Cancer Therapy

Advanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen, Jiaqi Chen, Yixuan Chen, Wenxuan Yuan, Jiao Zhang, Guoqing Wang, Zhuojun Dai   +6 more
wiley   +1 more source

The complement system in intestinal inflammation and cancer. [PDF]

J Clin Invest
Krieg C, Guglietta S.
europepmc   +1 more source

Next‐Generation Piezoelectric Materials in Wearable and Implantable Devices for Continuous Physiological Monitoring

Advanced Science, EarlyView.
An analysis of literature trends and a historical overview of organic and inorganic piezoelectric materials, focusing on their structural diversity, functional mechanisms, and inherent characteristics. It then explores cutting‐edge developments in material synthesis, fabrication processes, and performance optimization, highlighting their applicability ...
Bangul Khan, Umay Amara, Bilawal Khan, Wasim Ullah Khan, Rafi u Shan Ahmad, Muhammad Shehzad Khan, Mohamed Elhousseini Hilal, Bee Luan Khoo   +7 more
wiley   +1 more source

Mechanism of Regulation of NaCl Homeostasis in the Distal Colon During Obesity. [PDF]

Int J Mol Sci
Palaniappan B, Crutchley J, Paulraj RS, Borthakur A, Arthur S.   +4 more
europepmc   +1 more source

Highly Selective Exogenous Neutrophils Effectively Inhibit Growth of Colon Cancer under the Guidance of Precision Navigation. [PDF]

Research (Wash D C)
Yang Y, Li C, Shao Y, Wen X, Lu C, Gao X, Mei Y, Sun B.   +7 more
europepmc   +1 more source

Ileal J-Pouch interposition as a salvage technique for failed coloanal anastomosis: a case report. [PDF]

BMC Surg
Derakhshani S, Ghadim MK, Ashtari S.
europepmc   +1 more source