Results 281 to 290 of about 5,799,531 (403)

Right Versus Left Colon Cancer Biology: Integrating the Consensus Molecular Subtypes.

open access: yesThe Journal of the National Comprehensive Cancer Network, 2017
Michael S. Lee, D. Menter, S. Kopetz
semanticscholar   +1 more source

Treatment with curative intent for locoregional recurrent colon cancer - a systematic review. [PDF]

open access: yesBMC Surg
Rademaker E   +10 more
europepmc   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao   +14 more
wiley   +1 more source

Na,K-ATPase activity promotes macropinocytosis in colon cancer via Wnt signaling [PDF]

open access: gold
Nydia Tejeda‐Muñoz   +8 more
openalex   +1 more source

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

open access: yesAdvanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei   +10 more
wiley   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu   +16 more
wiley   +1 more source

Prognostic Immunological Factors of Lymphogenic Metastasis in Colon Cancer

open access: diamond
Oleg I. Kit   +12 more
openalex   +1 more source

Home - About - Disclaimer - Privacy