Results 291 to 300 of about 5,799,531 (403)

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

Advanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu, Peng Wang, Qing‐Hua Shen, Qi‐Xin Guan, Zhi‐Yuan Li, Ying‐Ying Han, Xin‐Yi Zhang, Qing‐Yuan Hu, Cai‐Ping Tan   +8 more
wiley   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

The emperor has no clothes-the need for standardized anatomical segment definitions in the management of colon cancer. [PDF]

Int J Colorectal Dis
Kutlu B, Benlice C, Seker ME, Kocaay AF, Kuzu MA.   +4 more
europepmc   +1 more source

Colitis-associated Colorectal Cancer Diagnosed after Descending Colon Perforation in a Patient with Crohn's Disease

Nobuhiro Naito, Tatsunari Fukuoka, Kishu KITAYAMA, Hiroaki Kasashima, Masatsune Shibutani, Kiyoshi Maeda   +5 more
openalex   +2 more sources

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

Advanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu, Ling Tang, Zheng Kuang, Danyi Huang, Ting Li, Gaofei Yin, Yingyu Chen, Wei Guo, Wenling Han, Pingzhang Wang   +9 more
wiley   +1 more source

A novel cuproptosis-related prognostic gene signature and validation of differential expression in colon cancer. [PDF]

Discov Oncol
Song Q, Yu Z, Wu Y, Huang P, Zhou R, Xu X.   +5 more
europepmc   +1 more source

Cytostatic Effect of a New Tropolone Derivative on the SW620 Colon Cancer Cell Line

Irina V. Mezhevova, S. Yu. Filippova, Татьяна Владимировна Чембарова, N. V. Gnennaya, Inna A. Novikova, А. С. Гончарова, С. Н. Димитриади, Shaposhnikov Av, Yu. A. Sayapin, E.A. Gusakov, Inna O. Tupaeva, Tatyana A. Krasnikova   +11 more
openalex   +1 more source

A Case of Metastatic Colon Cancer from Gastric Cancser with Ileus

, 2015
Atsuko Usuda, Kentaro Yamaguchi, Asako Shimazaki, Akira Miyaki, Minoru Murayama, Shinichi Asaka, Takeshi Shimakawa, Takao Katsube, Yoshihiko Naritaka, Mariko Fujibayashi   +9 more
openalex   +2 more sources

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

Advanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li, Dong Zhang, Eryu Peng, Shijun Shen, Hamid Alinejad‐Rokny, Yao Liu, Junke Zheng, Cizhong Jiang, Youqiong Ye   +8 more
wiley   +1 more source

Neoantigen dendritic cell vaccination combined with conventional chemotherapy for a patient with advanced transverse colon cancer. [PDF]

J Surg Case Rep
Onishi H, Higa A, Tasaki M, Inaoka Y, Okuda A, Miki Y, Tsuchida Y, Hino H, Kawamoto M, Ueda S, Takai N, Ando K, Tani M, Tani N, Ito T, Yamagishi H, Nakamura Y, Tani K.   +17 more
europepmc   +1 more source