Results 191 to 200 of about 77,748 (262)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Exploring the genetic heritage of Peru: an interview with Victor Borda. [PDF]

Commun Biol
europepmc   +1 more source

Indigenous women's health and data sovereignty: imagining an Indigenous research methodology using quantitative methods. [PDF]

AlterNative (Nga Pae Maramatanga (Organ))
Crosschild C, Varcoe C, Brown HJ, Browne AJ.   +3 more
europepmc   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Beyond geopolitics: Greenland's suicide crisis. [PDF]

Lancet Reg Health Eur
The Lancet Regional Health-Europe.
europepmc   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Political ecology: past, present, and future. [PDF]

Discov Sustain
Malik IH, Borde R, Ford JD.
europepmc   +1 more source

Correction to "Rescue and Translocation of Hispaniola Hutia (<i>Plagiodontia aedium</i>) in Pueblo Viejo, Cotuí Mining Concession Area". [PDF]

Ecol Evol
europepmc   +1 more source

A millennium of cold-water coral habitat loss in the East Pacific during low ENSO variability in the mid- to late Holocene. [PDF]

Proc Natl Acad Sci U S A
Stewart JA, Robinson LF, Taylor ML, Fornari DJ, Robert K, Banks S, Chen T, Li T, Kershaw J, Hoy S, Liu Q, Gordon JD, de Carvalho Ferreira ML, Samperiz A, Shen Y, Sun YJ, Wang M.   +16 more
europepmc   +1 more source

Decolonising and Diversifying Veterinary Education: Why It Matters and How to Begin. [PDF]

Vet Ophthalmol
Maini S.
europepmc   +1 more source