Results 201 to 210 of about 1,383,550 (260)

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

open access: yesAdvanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag   +3 more
wiley   +1 more source
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Colonialism, Coloniality, and Colonial Rule in Africa

2021
Using primary source documents of explorers, missionaries, colonialists, and extant literature, this chapter examines the underlying factors behind European colonial conquest of Africa, nature and structure of the different colonial systems imposed, and the impacts of colonial rule and coloniality on Africa.
openaire   +1 more source

Colonialism, stages of colonialism and the colonial state

Journal of Contemporary Asia, 1980
(1980). Colonialism, stages of colonialism and the colonial state. Journal of Contemporary Asia: Vol. 10, No. 3, pp. 272-285.
openaire   +1 more source

Colony

2017
This chapter analyzes concept of colony, which inhabits an ambiguous sort of space in its oscillation between the still neutrality of a common noun and a political concept in waiting, poised to discharge its potentiality. The conceptual work marshaled to maintain the colony as a political principle is protean, transitory, and contingent in its ...
openaire   +1 more source

Colonial Education

2019
This chapter considers colonial education as experienced by children of both colonists and the colonized in three quite different colonial contexts. It briefly considers the cases of schooling in the Dutch colony of the East Indies, the Japanese colony of Taiwan, and the British Australian colonies (and early Australian Commonwealth), focusing on the ...
openaire   +2 more sources

Colonialism and the Colonial Impact

1984
The pre-colonial history of Africa has been pieced together from archaeological findings, oral tradition, and the records of Arab and other alien chroniclers, such as Ibn Battuta, who travelled widely in the Muslim world in the fourteenth century. A good deal is now known, for example, of the richness of the Egyptian civilisation of the pre-Christian ...
openaire   +1 more source

Colonies - Colonisation - Colonialism

Ancient West & East, 2011
Colonies, colonisation and, in particular, colonialism are concepts carrying heavy ideological subtexts – yet they loom over the current debate about the dynamism of the Iron Age Mediterranean. Forty years after M.I. Finley’s ‘attempt at a typology’, this paper tries to thin out the terminological jungle: by employing cross-cultural historical ...
openaire   +1 more source

Settler Colonialism is not Colonialism

2015
In November 2011 Science published a paper presenting research conducted by a team led by population geneticist Laurent Excoffier of the University of Montreal. This work repackaged in a genetics-inflected language a recurring tenet of settler colonial discourse, a point initially suggested by the apologists of the settler ‘transition’ of the ...
openaire   +1 more source

Colony PCR

2017
Escherichia coli and Saccharomyces cerevisiae are currently the two most important organisms in synthetic biology. E.coli is almost always used for fundamental DNA manipulation while yeast is the simplest host system for studying eukaryotic gene expression and performing large scale DNA assembly.
Azevedo, Flávio   +2 more
openaire   +3 more sources

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