Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
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Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice
Aging and Cancer, EarlyView.Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth +7 more
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Are colon neoplastic lesions associated with stomach helicobacter pylori infection?
American Journal of Experimental and Clinical Research, 2014 A number of previous studies have shown that there is a correlation between Helicobacter Pylori (H. Pylori) and colorectal neoplasia. However, other studies could not prove whether there is a relation between the H.
Umıt Koc +6 more
doaj +2 more sources
Human medicines European public assessment report (EPAR): Capecitabine Teva, capecitabine, Colonic Neoplasms,Breast Neoplasms,Colorectal Neoplasms,Stomach Neoplasms, Date of authorisation: 20/04/2012, Revision: 10, Status: Authorised [PDF]
, 2019 Kernel Networks Inc.
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Aging and Cancer, EarlyView.Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang +17 more
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Reg IV in human body and diseases [PDF]
, 2012 Inflammatory bowel diseases (IBD) and cancers of the gastrointestinal (GI) tract cause considerable morbidity and mortality. In order to enhance the diagnostics and therapeutic measures, the biology of these diseases needs to be better understood ...
Maille, Kukka
core
Advanced Chinese Medicine, EarlyView.Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
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Liver resection for metastatic colorectal cancer [PDF]
, 1986 From 1975 to 1985, 60 patients with isolated hepatic metastases from colorectal cancer were treated by 17 right trisegmentectomies, five left trisegmentectomies, 20 right lobectomies, seven left lobectomies, eight left lateral segmentectomies, and three ...
Esquivel, CO +3 more
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Prediction of advanced colonic neoplasm in symptomatic patients: a scoring system to prioritize colonoscopy (COLONOFIT study) [PDF]
, 2019 Fernando Fernández‐Bañares +12 more
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Cytokine, Chemokine, and Neurofilament Light Chain Signatures in LGI1 Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To investigate the value of cytokine, chemokine, and neurofilament light chain (NfL) concentrations in predicting relapse risk, chronic epilepsy, and functional impairment in LGI1 autoimmune encephalitis (AE). Methods Cytokines/chemokines (IL‐1‐beta, IL‐2, IL‐4, IL‐5, IL‐6, IL‐8/CXCL8, IL‐10, IL‐12p70, IL‐13, IL‐17A, GM‐CSF, TNF ...
Albert Aboseif +17 more
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