Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Colonic actinomycosis: a pseudo-tumour that mimics colonic neoplasm [PDF]
K W, Hui, B S Y, Chan, K K Y, Yuen
openaire +2 more sources
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
Do a Positive Occult Fecal Blood Test and a Colonic Mass on Imaging Always Mean Colonic Neoplasm? A Case Report Describing the Rare Entity of Filiform Polyposis in an Asymptomatic Patient Who Underwent Colectomy for Suspected Colonic Neoplasm and Proposal of Strategies to Improve Diagnostic Acumen to Recognize This Rare Entity for the Purpose of Preventing Unnecessary Surgical Procedures Such as Colectomy [PDF]
Chrisy Mafnas +2 more
openalex +1 more source
TTF-1 positivity in Merkel cell carcinoma : the chosen clone matters [PDF]
Creytens, David
core +2 more sources
The article explores the discovery of unusually large, ring‐shaped ESCRT protein structures formed by immune and stromal cells. It investigates their formation, composition, and potential roles in immune synapse formation. The findings challenge assumptions about their function in immunological synapses, suggesting an exclusive role in maintaining ...
Anthi Psoma +3 more
wiley +1 more source
The expression of claudins in colonic neoplasms
Н. А. Олейникова +3 more
openalex +1 more source

