Results 81 to 90 of about 337,461 (300)

Colonic Protein Fermentation and Promotion of Colon Carcinogenesis by Thermolyzed Casein [PDF]

, 1995
Thermolyzed casein is known to promote the growth of aberrant crypt foci (ACF) and colon cancer when it is fed to rats that have been initiated with azoxymethane.
Thompson, Lilian, Bruce, W. Robert, Archer, Michael C., Rémésy, Christian, Medline, Alan, Corpet, Denis E.   +5 more
core  

CONSORT diagram with survey-weighted estimates.

, 2023
Of 2,149,280 hospitalizations for colectomy identified in the 2012–2019 NIS, 569,280 patients were included for analysis. Of these, 153,435 (27.0%) were for benign colonic neoplasms. All estimates represent survey-weighted methodology.
Millicent Croman (17283488), Sara Sakowitz (14076650), Saad Mallick (17283479), Hanjoo Lee (12967802), Baran Khoraminejad (17283482), Manuel Olmedo (17283485), Syed Shahyan Bakhtiyar (14076653), Peyman Benharash (2837768)   +7 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Colon lesions in elderly individuals with positive and negative fecal immunochemical test results among PERSIAN Guilan cohort study (PGCS) population [PDF]

Caspian Journal of Internal Medicine
Background: Early colorectal cancer (CRC) detection helps reduce the mortality rate. This study aimed to investigate colon lesions in individuals with positive and negative fecal immunochemical test (FIT) results among the (PERSIAN) Guilan cohort study ...
Heydar Ali Balou, Farahnaz Joukar, Mahdi Orang Goorabzarmakhi, Milad Shahdkar, Soheil Hassanipour, Saman Maroufizadeh, Mehrnaz Asgharnezhad, Paridokht Karimian, Fariborz Mansour-Ghanaei   +8 more
doaj  

Colonic fermentation – more than meets the nose [PDF]

, 2009
Fermentation of undigested foods in the colon by its resident bacteria affects not only colonic health (protection against inflammation and tumour formation) but also influences metabolic health.
Arasaradnam, Ramesh P., Pharaoh, Mark W., Nwokolo, Chuka U., Bardhan, Karna Dev, Williams, Geraint J., Kumar, Sudhesh   +5 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Mucosubstances in neoplasms of the human colon and rectum [PDF]

Gut, 1971
The patterns of mucosubstances secreted in the normal human colon and rectum, in benign tumours, and in and around malignant tumours of the colon and rectum have been studied. Very little neutral mucosubstance was seen in normal specimens; the secretion in these was made up of sulphated and nonsulphated acid mucosubstances, with the ...
openaire   +2 more sources

Distal colonic neoplasms predict proximal neoplasia in average-risk, asymptomatic subjects

, 1999
Flexible sigmoidoscopy has been recommended as a screening method to reduce the incidence of colorectal cancer in asymptomatic, average-risk subjects through the early detection and removal of polyps.
Platell, C., Aquilia, S., Olynyk, J., Collett, J., Fletcher, D.   +4 more
core  

Accumulation of promutagenic DNA adducts in the mouse distal colon after consumption of heme does not induce colonic neoplasms in the western diet model of spontaneous colorectal cancer [PDF]

, 2013
Author version made available in accordance with Publisher copyright policy.Scope: Red meat is considered a risk factor for colorectal cancer (CRC). Heme is considered to promote colonic hyperproliferation and cell damage. Resistant starch (RS) is a food
Young, Graeme Paul, Winter, Jean, Hu, Ying, Gratz, Silvia W, Le Leu, Richard Kevin, Conlon, Michael A   +5 more
core   +1 more source