Results 141 to 150 of about 15,828 (233)

Cost‐Effectiveness Analysis of Fecal Immunochemical Test‐ and Colonoscopy‐based Colorectal Cancer Screening across Varying Uptake Rates

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives To reduce the burden of colorectal cancer (CRC), identifying cost‐effective screening strategies with particular attention to screening adherence is essential. We aimed to assess the cost‐effectiveness of screening strategies using fecal immunochemical test (FIT) and/or total colonoscopy (TCS) through simulation model analyses using
Masau Sekiguchi, Ataru Igarashi, Minoru esaki, Yutaka saito, Nozomu Kobayashi, Takahisa Matsuda   +5 more
wiley   +1 more source

Colon Polyps [PDF]

JAMA, 2008
openaire   +2 more sources

Comparison of Detection Yields Between Texture and Color Enhancement Imaging Mode 1 and Mode 2 for Colorectal Lesions: A Post‐hoc Analysis of a Multicenter Observational Study

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Colonoscopy is a reliable technique for the detection, diagnosis, and treatment of adenomas and early cancer. Image‐enhanced endoscopy (IEE) is important for detecting colorectal lesions. Texture and color‐enhancement imaging (TXI) has recently emerged as a novel modality for IEE.
Kensuke Shinmura, Hiroaki Ikematsu, Taku Sakamoto, Maasa Sasabe, Tatsuro Murano, Yasuhiko Mizuguchi, Hiroyuki Takamaru, Toshiki Futakuchi, Naoto Tamai, Kazuki Sumiyama, Yutaka Saito   +10 more
wiley   +1 more source

Adalimumab‐responsive Monogenic Inflammatory Bowel Disease With Pseudopolyposis Characteristic of TGFBR2 Variant in Loeys‐Dietz Syndrome

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Loeys‐Dietz syndrome (LDS) is an autosomal dominant connective tissue disorder caused by pathogenic variants in TGFBR1 or TGFBR2. It is characterized by vascular fragility, skeletal abnormalities, and predisposition to allergic and inflammatory conditions, including monogenic inflammatory bowel disease (IBD).
Tomomitsu Sado, Satoshi Ukai, Shingo Kurasawa, Yosuke Kono, Norio Hasuda, Mai Iwaya, Takaya Nakane, Tomomi Yamaguchi, Tomoki Kosho, Yoshiko Nakayama   +9 more
wiley   +1 more source

Clinicopathological Features of Superficial Non‐Ampullary Duodenal Epithelial Tumors Involving Brunner's Glands

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Background and Aims Although Brunner's glands (BGs), located in the submucosa of the duodenum, may be involved by tumor cells of superficial non‐ampullary duodenal epithelial tumors (SNADETs), the detailed incidence and histopathological features have not yet been analyzed. This study aimed to clarify the histopathological relationship between
Kazuki Takayama, Taro Iwatsubo, Mitsuaki Ishida, Shun Sasaki, Akitoshi Hakoda, Noriaki Sugawara, Kazuhiro Ota, Toshihisa Takeuchi, Nao Kawaguchi, Atsushi Tomioka, Ryo Tanaka, Mitsuhiro Asakuma, Sang‐Woong Lee, Kazuhide Higuchi, Yoshinobu Hirose, Hiroki Nishikawa   +15 more
wiley   +1 more source

Feasibility Study of Modified Underwater Endoscopic Mucosal Resection for Colorectal Polyps

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Underwater endoscopic mucosal resection (UEMR) is widely performed for colorectal tumors. However, in our experience, it is sometimes difficult to keep a clear endoscopic view underwater, due to dirty fluid inflow or insufficient water pooling after grasping the polyp, or bleeding just after endoscopic resection.
Kaizo Kagemoto, Koichi Okamoto, Yoji Takeuchi, Yasuyuki Okada, Motoko Sei, Shota Fujimoto, Ryo Shinomiya, Takeshi Mitsuhashi, Takanori Yoshimoto, Reiko Yokoyama, Tomoyuki Kawaguchi, Yoshifumi Kida, Yasuhiro Mitsui, Yutaka Kawano, Masahiro Sogabe, Hiroshi Miyamoto, Yasushi Sato, Tetsuji Takayama   +17 more
wiley   +1 more source

KRAS‐G12C: The neglected biomarker to detect patients with MUTYH‐associated polyposis

International Journal of Cancer, Volume 158, Issue 6, Page 1588-1598, 15 March 2026.
What's new? MUTYH‐associated polyposis is an underdiagnosed recessive syndrome that predisposes individual to colorectal cancer and frequently displays KRAS‐G12C mutations. By analyzing a large cohort of colorectal cancer patients routinely tested for KRAS, the authors assessed whether KRAS‐G12C detection could serve as a pre‐screening tool for the ...
Ana Beatriz Deleame Medeiros, Gabriel Oliveira dos Santos, José Claudio Casali‐da‐Rocha, Samuel Aguiar Junior, Virgilio Souza e Silva, Gustavo Nóriz Berardinelli, Augusto Perazzolo Antoniazzi, Rui Manuel Reis, Dirce Maria Carraro, Giovana Tardin Torrezan   +9 more
wiley   +1 more source

Exploring the Key Role of Nanotechnology on Intratumoral Microbiome Modulation for Cancer Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
The review provides a comprehensive analysis of microbiome‐mediated oncogenic mechanisms in various cancers, emphasizing the unique therapeutic strategies facilitated by nanotechnology. It aims to fill this gap by systematically reviewing nanotechnology‐driven strategies for microbiome elimination, with a focus on their ability to improve the cold TME ...
Yumei Gan, Yan Zhang, Xia Dong, Feng Lv
wiley   +1 more source

High Risk of Colorectal Cancer After High‐Grade Dysplasia in Inflammatory Bowel Disease Patients

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 5, Page 706-714, March 2026.
The advantages of colon‐sparing treatment for high‐grade dysplasia should be weighed against the higher risk of metachronous colorectal cancer and the subsequent need for stringent endoscopic surveillance. ABSTRACT Background There are limited data on colorectal cancer (CRC) risk after high‐grade dysplasia in inflammatory bowel disease.
Monica E. W. Derks, Maarten te Groen, Lauranne A. A. P. Derikx, Iris D. Nagtegaal, Frank Hoentjen   +4 more
wiley   +1 more source

Gastroenterological disorders and hepatic disease in adults with cerebral palsy: A systematic review

Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 313-331, March 2026.
Abstract Aim To describe the incidence, prevalence, and prognostic factors for gastroenterological disorders and hepatic disease in adults with cerebral palsy (CP), and to examine the effectiveness of any screening or interventions. Method Six databases were searched for articles published in any language since 1990 meeting eligibility criteria ...
Christina M. Marciniak, Jennifer M. Ryan, Alejandra Camacho‐Soto, Emily Capellari, Jessica Burke, Maram Sofiany, Zoë Post, Eric C. Sung, Michael D. Brown, the Adult Cerebral Palsy Clinical Practice Guidelines Working Group, Jennifer M Ryan, Rachel Byrne, Emily Capellari, Donna Riccio Omichinski, Mark Peterson, Jan Willem Gorter, Ashley Harris Whaley, Christine Imms, Christina M. Marciniak   +18 more
wiley   +1 more source