Results 81 to 90 of about 140,238 (232)

What Is the Evidence Base Regarding Early Onset Colorectal Cancer in Australia and New Zealand? A Scoping Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Early onset colorectal cancer (EoCRC), commonly defined as colorectal cancer diagnosed in people under 50 years of age, is increasing in incidence in Australia and New Zealand. The underlying cause of this remains unclear, despite its growing public health importance.
Tiffany J. Cherry, Dilshan Udayasiri, Ian P. Hayes   +2 more
wiley   +1 more source

Adaptive Spaces and Rural Futures: Climate Change, Agrarian Dynamics, and Knowledge Politics in Southeast Asian Socioecological Transformations

Asia Pacific Viewpoint, EarlyView.
ABSTRACT Contemporary rural change in Southeast Asia is shaped by complex, intersecting forces that defy simplistic narratives. Researchers must therefore develop new ways to grasp nuanced, non‐linear, and locally specific processes to understand how transformational shifts may occur (or not) in the region.
John F. McCarthy, Jean‐Christophe Castella, Kelly Dorkenoo   +2 more
wiley   +1 more source

Real‐World Safety and Efficacy of Pola‐R‐CHP in Previously Untreated DLBCL: POLASTAR Interim Analysis of 500 Patients

Cancer Science, EarlyView.
In this analysis of a diverse cohort of 500 patients with previously untreated DLBCL in a real‐world clinical setting, Pola‐R‐CHP demonstrated high response rates at end‐of‐treatment, which were consistent among the overall population, in patients > 80 years and regardless of International Prognostic Index status and cell of origin subtypes.
Takahiro Kumode, Hitomi Sawa, Kohta Miyawaki, Atsushi Satake, Nobuhiro Kanemura, Ritsuro Suzuki, Yuki Fujiwara, Yasuhiro Nagate, Shuichi Ota, Takahiro Fujino, Hideki Goto, Noriko Fukuhara, Mamiko Sakata‐Yanagimoto, Koji Izutsu, Momoko Nishikori, Hirohiko Shibayama, Daisuke Ennishi, Takayuki Shimose, Mai Asai, Itaru Matsumura, Koichi Akashi, Koji Kato   +21 more
wiley   +1 more source

Poliposis linfomatosa intestinal

Medisan
Se expone el caso clínico de un paciente de 55 años de edad, de piel blanca, que acudió a la consulta de Gastroenterología por presentar diarreas desde hacía alrededor de un año, dolor abdominal difuso, pérdida de peso, astenia y anorexia.
Cesar Falagán Andina, Elba Patricia Cabezas Niubó, Inocente Rodríguez Reyes, Lilibet Zamora Cabezas, Jesús Fernández Duharte   +4 more
doaj  

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

A Rare Case of Familial Adenomatous Polyposis in South Eastern Nigeria: A Case Report and Review of the Literature

International Journal of Medicine and Health Development
Familial adenomatous polyposis syndrome (FAP) is a rare multisystemic disorder that affects individuals who have mutation in the adenomatous polyposis coli (APC) gene.
Kenneth A. Agu, Jude K. Ede, EvanTherese Nwosu, Ikechukwu S. Eze, Emeka Eze, Chukwuemelie B. Okechukwu, Ifeoma Madichie   +6 more
doaj   +1 more source

Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology

Histopathology, EarlyView.
The definition of the colorectal traditional serrated adenoma (TSA) has evolved to recognize a broader morphological spectrum, including classical, flat and mixed lesions reflecting early development and neoplastic progression. Updated WHO classification highlights the need for consistent terminology to improve recognition and to distinguish TSA from ...
Christophe Rosty, Maurice B. Loughrey, Taiki Hashimoto, Markus Mäkinen, Rish K. Pai, Shigeki Sekine, Rhonda K. Yantiss, Iris D. Nagtegaal   +7 more
wiley   +1 more source

Is Routine Interruption of Direct Oral Anticoagulants Necessary during Colorectal Endoscopic Mucosal Resection and Hot Snare Polypectomy? A Multicenter Propensity‐Matched Study

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aims Colorectal endoscopic mucosal resection (EMR) and hot snare polypectomy (HSP) are high‐bleeding‐risk endoscopic procedures, and most clinical guidelines recommend stopping direct oral anticoagulants (DOACs) temporarily or switching to heparin‐bridging therapy (HBT). However, existing evidence is largely derived from cohorts
Yutaka Okagawa, Masanori Sato, Masahiro Hirakawa, Shogo Miura, Naotaka Hayasaka, Yusuke Tomita, Saki Ameda, Ginji Omori, Shutaro Oiwa, Akira Sakurada, Tomoyuki Abe, Shinya Minami, Tetsuya Sumiyoshi, Yasuhiro Nagaoka, Hiroyuki Hisai, Shinichi Katsuki, Kohichi Takada   +16 more
wiley   +1 more source

The Association between Anthropometric Indicators and Colorectal Polyps and Diverticulosis

Journal of Coloproctology
Introduction Colonic polyps and diverticulosis are common colon findings on colonoscopy. One of the risk factors of colorectal polyps and diverticulosis is the anthropometric index.
Sahar Najafi Mobaraki, Farahnaz Joukar, Saman Maroufizadeh, Massood Baghaee, Mehrnaz Asgharnezhad, Fariborz Mansour-Ghanaei   +5 more
doaj   +1 more source

The Synergy Between a Silver‐Ruthenium Antimicrobial and Aminoglycosides Is Based on Severe Macromolecular Damage

Molecular Microbiology, EarlyView.
AGXX enhances aminoglycoside activity against multidrug‐resistant pathogens such as uropathogenic Escherichia coli by increasing reactive oxygen species, causing protein aggregation and DNA damage. This effect is reduced by oxygen limitation or antioxidants. Polyphosphate protects cells from oxidative damage.
Emmanuel P. Oladokun, Gracious Y. Donkor, Julius K. Narh, Grady D. Jacobson, Cade Ward, Patrick O. Tawiah, Lisa K. Polzer, Kevin A. Edwards, Kyle A. Floyd, Jan‐Ulrik Dahl   +9 more
wiley   +1 more source