Results 171 to 180 of about 79,045 (322)

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Dispersion and new shelters offered by ants: myrmecophoresy of tardigrades. [PDF]

Front Zool
Giannetti D, Giovannini I, Massa E, Schifani E, Rebecchi L, Guidetti R, Grasso DA.   +6 more
europepmc   +1 more source

CypA Mediates Non‐Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11

Advanced Science, EarlyView.
Summary diagram for the role of CypA in chemoresistance in non‐small cell lung cancer (NSCLC). CypA is overexpressed in chemoresistance NSCLC and drives therapeutic evasion by competitively binding to the K37 site of SLC7A11, thereby blocking TRIM3 mediated K11‐linked ubiquitination and proteasomal degradation, ultimately inhibiting lipid peroxidation ...
Zhongcheng Wang, An Li, Ziwei Song, Xiangming Liu, Yong Ge, Zhiqiao Chen, Yuhui Liu, Boyu Zhang, Hao Zhang, Ting Lan   +9 more
wiley   +1 more source

Dual microbial inoculation for tripartite benefits: soybean biomass enhancement, root rot control and chlorothalonil residue reduction. [PDF]

Front Plant Sci
Jie W, Zhang M, Tan Y, Yang H, Wang W, Kan L.   +5 more
europepmc   +1 more source

Nature‐Inspired Innovation in Electrical Engineering Technologies and Applications

Advanced Science, EarlyView.
This review investigates how nature‐inspired design principles revolutionize electrical engineering by translating biological mechanisms, such as sensing, actuation, energy conversion, and neural processing, into advanced intelligent technologies. Through interdisciplinary integration, biomimetic strategies enable efficient, adaptive, and sustainable ...
Ming Li, Anran Mao, Qingwen Guan, Yang Xu, Chang Li, Gang Lu, Eduardo Saiz   +6 more
wiley   +1 more source

Murine Models of Klebsiella pneumoniae Gastrointestinal Infection. [PDF]

Curr Protoc
Valencia-Bacca JD, Islam MM, Haas KM, Zafar MA.   +3 more
europepmc   +1 more source

Effect of a screening dose of HE (¼ IC₅₀ in the viability assay) on the colonization ability of pretreated MCF-7 breast cancer and HCT-116 colorectal cancer cells in colony formation. The figure showed representative images of the ability of the surviving cells to form colonies in the treatment group compared to the vehicle control.

Eman M. El-Deeb (14571719), Fatma A. Moharram (9276104), Hussein S. Taha (14571722), Mohamed R. Elgindi (14571725), Kuei-Hung Lai (3226101), Hassan Y. Ebrahim (3800953), Heba E. Elsayed (3800956)   +6 more
openalex   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Is it time to assign <i>Lactiplantibacillus plantarum</i> as a keystone species in the <i>Drosophila melanogaster</i> microbiota? [PDF]

Appl Environ Microbiol
Chaston JM.
europepmc   +1 more source

Plant and Breeding Bird Communities of Black-Tailed Prairie Dog Colonies and Non-Colonized Areas in Southwest Kansas and Southeast Colorado

, 1999
Stephen L. Winter
openalex   +1 more source