Results 181 to 190 of about 71,581 (290)

Inactivation of Cysteine Synthase CysK-A enhances flocculation, biofilm formation, and sensitivity to oxidative stress in <i>Azospirillum brasilense</i> Sp7. [PDF]

Biofilm
Herrera-Galindo J, Alcantara-Rosales CA, Ojeda OM, Xiqui-Vázquez ML, Mancilla-Simbro C, Reyes-Carmona S, Baca BE, Ramírez-Mata A.   +7 more
europepmc   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Host-associated beneficial gut microbiota boosts induced immunity and limits immune deployment costs in bumblebees. [PDF]

J Anim Ecol
Calhoun AC, Shosanya T, Long BK, Rehberger JK, Sadd BM.   +4 more
europepmc   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

<i>Penicillium</i> and <i>Talaromyces</i> diversity in cystic fibrosis patient sample and the description of a new species, <i>Penicillium subluteum</i> sp. nov. (Eurotiales, Aspergillaceae). [PDF]

MycoKeys
Zhou YB, Meijer EFJ, Engel TGP, Wang QM, Feng ZX, Hagen F, Meijer M, Kraak B, Meis JF, Houbraken J.   +9 more
europepmc   +1 more source

Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro

Advanced Science, EarlyView.
A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner, Petra B. Welzel, Maximilian Fusenig, Linda Sturm, Dagmar Pette, Wolfgang Wagermaier, Claudia Fischbach, Peter Fratzl, Carsten Werner   +8 more
wiley   +1 more source

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

Advanced Science, EarlyView.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong, Hang Zhou, Chenyang Ye, Lei Chu, Lin Wang, Yingjun Wang   +5 more
wiley   +1 more source

Ventilator-associated lower respiratory tract infections and bacteremia in medical and surgical critical care patients colonized by multidrug-resistant bacteria. [PDF]

BMC Infect Dis
Torres I, Ferrer J, Colomina J, Clari MÁ, Olea B, Giménez E, Albert E, Sánchez-Jordán P, Aguilar G, Carbonell N, Navarro D.   +10 more
europepmc   +1 more source

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Advanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao   +10 more
wiley   +1 more source

Molecular Characterisation of Fungi Populations in the Chronic Wounds of Filarial Lymphedema Patients in Southern Ghana: A Cross-Sectional Study. [PDF]

Health Sci Rep
Ayeke DY, Osei-Poku P, Byamukama D, Amewu EKA, Abakah A, Shardow ALK, Yeboah SMA, Antwiwaa C, Wilson MB, Wireko S, Larbi A, Kwarteng A.   +11 more
europepmc   +1 more source