Results 191 to 200 of about 71,581 (290)

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

Advanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács, Durga Prasad, Vic De Roo, Matthias Vanheede, Penthip Muangkaew, Annemieke Madder, Monica Höfte, René De Mot, Niels Geudens, José C. Martins   +9 more
wiley   +1 more source

Glutamate dehydrogenase 2 is required for virulence by facilitating fungal growth in the host hemocoel. [PDF]

Virulence
Lu Y, Wu D, Hu J, Peng G, Zhong J, Liu Y, Li J, Gao Q, Yu XQ.   +8 more
europepmc   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Dual microbial inoculation for tripartite benefits: soybean biomass enhancement, root rot control and chlorothalonil residue reduction. [PDF]

Front Plant Sci
Jie W, Zhang M, Tan Y, Yang H, Wang W, Kan L.   +5 more
europepmc   +1 more source

Gravity‐Tolerant In‐Flight 3D Bioprinting Enabled by Stereolithography for Space Tissue Engineering

Advanced Science, EarlyView.
A flight‐compliant, closed stereolithographic 3D bioprinting system enables robust fabrication of acellular and cell‐laden hydrogel constructs under varying gravitational conditions, including microgravity and hypergravity phases. Printed structures retain dimensional fidelity and high‐resolution features, while cell viability remains high ...
Bianca Lemke, Matthias R. Kollert, Tobias Lam, Tobias Thiele, Nicolas Göbel, Lisa R. Köhn, Gabriela Korus, Lutz Kloke, Georg N. Duda   +8 more
wiley   +1 more source

Dispersion and new shelters offered by ants: myrmecophoresy of tardigrades. [PDF]

Front Zool
Giannetti D, Giovannini I, Massa E, Schifani E, Rebecchi L, Guidetti R, Grasso DA.   +6 more
europepmc   +1 more source

Construction of Skin‐Adaptable Slide‐Ring Hydrogels Based on Bile Acids Derived Polyrotaxanes for Smart Wound Dressing

Advanced Science, EarlyView.
A novel β‐cyclodextrin/bile acid‐based slide‐ring hydrogel was prepared via precise host–guest recognition and photopolymerization. This smart hydrogel dressing exhibited skin‐adaptive mechanical properties, pH‐responsive antibacterial activity, and integrated multi‐signal sensing (temperature, blood, and pressure) for advanced wound management ...
Wen Huang, Xueru Xiong, Qian Sun, Xiangting Lai, Lili Cai, Yunhua Chen, Lin Wang, Yong‐Guang Jia   +7 more
wiley   +1 more source

The pcnB gene sustains Shigella flexneri virulence. [PDF]

PLoS Pathog
Frisch T, Geiser P, Komi M, Karlsson PA, Bhetwal A, Jenniches L, Barquist L, Holmqvist E, Mateus A, Sellin ME, Di Martino ML.   +10 more
europepmc   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Protocol for determining gut microbiota metabolites as substrates in mouse metabolism. [PDF]

STAR Protoc
Fang H, Kukje Zada D, Barra NG, Rodrigues E-Lacerda R, Schertzer JD.   +4 more
europepmc   +1 more source