Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Emergent behavior of soil fungal dynamics:influence of soil architecture and water distribution [PDF]
, 2012 Macroscopic measurements and observations in two-dimensional soil-thin sections indicate that fungal hyphae invade preferentially the larger, air-filled pores in soils. This suggests that the architecture of soils and the microscale distribution of water
Baveye, Philippe C. +3 more
core +3 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The colonisation of Setswana: A decolonial rereading of the 1840 Gospel of Luke
HTS Teologiese Studies/Theological StudiesIn his 1840 translation of the Gospel of Luke from English into Setswana, Robert Moffat transfers Western numerals, geographic words and biblical names to Setswana.
Itumeleng D. Mothoagae
doaj +1 more source
Enumeration, identification and characterisation of methanogens colonising pre-ruminant calves : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science at Massey University, Palmerston North, New Zealand [PDF]
, 2007 Methane-producing archaea, methanogens, in ruminant animals are a major source of anthropogenic methane. With a global warming potential 23 times greater than carbon dioxide, methane has been targeted for reduction under the Kyoto protocol.
Evans, Paul Nicolas
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
De la production paysagère à la formation des paysages vécus à Conakry (Guinée)
Projets de Paysage, 2019 In Conakry, a capital city shaped ex nihilo, pre-colonial landscapes within the city were erased. At the end of the nineteenth century, the colonial administration designed and created landscapes which, at the time of Independence gave way to new social ...
Julie Gangneux-Kebe
doaj +1 more source
The Indian Northeast: India’s Shift from Colonised to Coloniser
Global Change, Peace & Security, 2020 The introduction of The Citizenship Amendment Act (CAA) and the National Register of Citizens (NRC) by Narendra Modi’s Bharatiya Janata Party (BJP) has sparked a collective resistance that has not been witnessed since the fight for Indian Independence.
openaire +2 more sources
Placement and displacement : the fallen woman in discourse : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in English at Massey University [PDF]
, 1993 This thesis is an invitation to reconsider the process of reading and representing the fallen woman. It combines an eclectic theoretical approach, drawing on works by Foucault, Derrida and Kristeva, with the metaphor of colonisation and the palimpsest ...
Dacre, Anna
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source