Results 51 to 60 of about 170,422 (284)

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Nonobstructing Colonic Dilatation and Colon Perforations Following Renal Transplantation [PDF]

, 1990
Nonobstructing colonic dilatation has not been commonly reported following renal transplantation, and colon perforations carry a high morbidity and mortality in this population.
Hakala, TR, Koneru, B, O'hair, DP, Selby, R, Starzl, TE, Tzakis, AG   +5 more
core   +1 more source

The New Kids on the Block: Emerging Complementary Colonoscopy Quality Metrics [PDF]

, 2022
Angela Y. Lam, Jeffrey K. Lee
openalex   +1 more source

Artificial intelligence‐enabled digital biomedical engineering

BMEMat, EarlyView.
This review presents a comprehensive overview, emphasizing the critical role of artificial intelligence (AI) in biomedical engineering. It further explores the implications of AI for future biomedical research and clinical practice, aiming to provide theoretical insights for academic investigation and technological innovation in the field.
Peiran Song, Xuan Tang, Xukun Lv, Rui L. Reis, Xiao Chen, Long Bai, Jiacan Su   +6 more
wiley   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

Cancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang, Na Qin, Fenfen Ji, Hao Su, Haiyun Shang, Hongyan Chen, Dan Huang, Qing Li, Jing Ren, Weixin Liu, Yifei Wang, Wei Kang, Jiabin Wu, Chi‐Chun Wong, Zongwei Cai, Matthew Tak Vai Chan, William Ka Kei Wu, Jun Yu, Huarong Chen   +18 more
wiley   +1 more source

The INSPECTOR study: enhanced feasibility for clinical translation of a multi‐cancer early detection method based on enzyme‐assisted high signal‐to‐noise ratio sequencing of methylated circulating tumor DNA

Cancer Communications, EarlyView.
Abstract Background Blood‐based cell‐free DNA (cfDNA) methylation testing has emerged as a promising approach for multi‐cancer early detection (MCED), holding the potential to improve cancer survival rates. However, traditional bisulfite‐based methods often encounter sensitivity limitations in detecting early‐stage malignancies or certain cancer types.
Hui‐Yan Luo, Wei Wei, Pansong Li, Qi‐Hua Zhang, Zhipeng Zhou, Liang Cui, Yong‐Bin Lin, Hong Yang, Xianyu Zhong, Qingfeng Liu, Han Yang, Kong‐Jia Luo, Hai‐Bo Qiu, Shu‐Qiang Yuan, Yuan‐Fang Li, Zhi‐Wei Zhou, Xiao‐Jun Lin, Bo‐Kang Cui, Rong‐Xin Zhang, Wen‐Hua Fan, He Huang, Chun‐Yan Lan, Jun‐Dong Li, Zhi‐Qiang Wang, Bin‐Kui Li, Rong‐Ping Guo, Jun Tang, Xin Huang, Mian Xi, Yuying Liu, Chuanbo Xie, Shi Chen, Zhi‐Hu Li, Yu‐Hua Liu, Xiao‐Ting Zhang, Qiang Zeng, Xin Yi, Rui‐Hua Xu   +37 more
wiley   +1 more source

Risk of advanced adenoma detection in colorectal cancer screening programmes according to personal characteristics and screening history

International Journal of Cancer, EarlyView.
What's New? Detection of advanced adenomas (AA) is a key indicator of clinical benefit in colorectal cancer screening programs (CRCSPs). Multiple factors, however, may influence the likelihood of AA detection. This study investigated AA detection in the context of factors related to personal screening history and social characteristics among ...
Mercedes Vanaclocha‐Espí, Paula Romeo‐Cervera, Susana Castan‐Cameo, Elena Pérez‐Sanz, Josefa Ibañez, Cristóbal Llorens‐Ivorra, Ruth Risueño‐Albuixech, María Besó, Ana Molina‐Barceló   +8 more
wiley   +1 more source

Crowdsourcing for Identification of Polyp-Free Segments in Virtual Colonoscopy Videos

, 2017
Virtual colonoscopy (VC) allows a physician to virtually navigate within a reconstructed 3D colon model searching for colorectal polyps. Though VC is widely recognized as a highly sensitive and specific test for identifying polyps, one limitation is the ...
Baker, Kevin, Barish, Matthew, Kaufman, Arie, Marino, Joseph, Mirhosseini, Seyedkoosha, Nadeem, Saad, Park, Ji Hwan   +6 more
core   +1 more source

Optimizing colonoscopy‐based colorectal cancer screening by low‐barrier, low‐threshold pretesting

International Journal of Cancer, EarlyView.
What's New? Although colonoscopy is widely considered the gold standard for colorectal cancer (CRC) screening, it is an invasive procedure with varying adherence rates that potentially leave many high‐risk individuals unscreened. Here, the authors assessed an optimized gateopener approach to improving CRC screening efficiency using a low‐threshold ...
Thomas Heisser, Rafael Cardoso, Tobias Niedermaier, Michael Hoffmeister, Hermann Brenner   +4 more
wiley   +1 more source

Colorectal Cancer Screening Quality Improvement: A FITKit Mailing Initiative [PDF]

, 2019
According to the American Cancer Society, colorectal cancers are diagnosed in 1 in 22 men and 1 in 24 women in their lifetime. Despite the wide range of effective CRC screening options available in the US, the Hudson Headwaters Health Network (HHHN) has ...
Kratzer, Isabella
core   +1 more source