Results 81 to 90 of about 55,115 (283)

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

Advanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu, Wenqin Wang, Shuyun Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, Heng Liu, Kyoichi Isono, Youming Zhang, Jingjing Cao, Xiangzhi Li   +12 more
wiley   +1 more source

IL‐7R‐Enriched Extracellular Vesicles From the Thymus Drive Colitis via Promoting Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao, Yuheng Liu, Ruibing Yang, Zifeng Zhu, Junwei Wu, Dinghao Li, Jin Su, Yingxin He, Shiqi Luo, Feiyang Cao, Haiyi Deng, Lanmengxi Yang, Ling Zhong, Peiying Peng, Xinyi Wu, Chunmei Cai, Zhen Li, Yujin Wu, Shuofeng Zhu, Jie Wei, Yi Yang, Lifu Wang   +21 more
wiley   +1 more source

Dish Washing Techniques on Colony Count of Cutleries in Food (Coto) Stall in Ternate [PDF]

There were two food poisoning incidences in 2023 in Ternate City. The presence of germs, can cause illness and even poisoning. Microbial load on cutleries could be caused by improper dish washing.
Sidebang, Purnama, Sakriani, Sakriani, Melinda, Aulia, Sangadjisowohy, Idayani   +3 more
core  

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Quantification methods of Candida albicans are independent irrespective of fungal morphology

Microbial Cell
The ability of Candida albicans to switch its morphology from yeast to filaments, known as polymorphism, may bias the methods used in microbial quantification.
Amanda B Soares, Maria C de Albuquerque, Leticia M Rosa, Marlise I Klein, Ana C Pavarina, Paula A Barbugli, Livia N Dovigo, Ewerton G de O Mima   +7 more
doaj   +1 more source

INVESTIGATION OF MICROBIAL COUNT IN THE SOIL AND EARTHWORM GUT (EUDRILUS EUGENIAE) [PDF]

, 2016
 The soil microbes are highest in compared with earthworm gut of  Eudrilus eugeniae. Microbes are soaring numbers of present in middle gut and several nutrients are gift within the soil.
V, SAKTHIDASAN, V, TAMIZHAZHAGAN, K, PUGAZHENDY, K, REVATHI, M, BARANITHARAN   +4 more
core   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Environmental Monitoring in a Class D Pharmaceutical Facility: Microbial Load and Hygiene Practices, a Risk-Based Cross-Sectional Study [PDF]

Background: Environmental monitoring is a crucial current Good Manufacturing Practice (cGMP) tool for assessing the status of the working environment in a Pharmaceutical Manufacturing Facility. Methods: The test was conducted between May 20 and 25, 2025.
Singh, Shrawan
core   +2 more sources

Physicochemical properties, microbial profile, and biogenic amines content of barramundi (Lates calcarifer Bloch) fillets wrapped in selected packaging films under modified atmosphere packaging [PDF]

, 2016
The purpose of this study was to investigate the effect of packaging film on physicochemical properties, microbial profile, and biogenic amines content of barramundi (Lates calcarifer Bloch) fillets packed in polyamide, polypropylene, and low-density ...
Abu Bakar, Fatimah, Yassoralipour, Ali, Bakar, Jamilah, Abdul Rahman, Russly   +3 more
core   +1 more source