Results 91 to 100 of about 941,860 (298)

Web page classification with an ant colony algorithm [PDF]

, 2004
This paper utilizes Ant-Miner - the first Ant Colony algorithm for discovering classification rules - in the field of web content mining, and shows that it is more effective than C5.0 in two sets of BBC and Yahoo web pages used in our experiments.
Holden, Nicholas, Alex A. Freitas, Freitas, Alex A., Nicholas Holden   +3 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Differential Leucocyte Count and Total Colony Count Changes in Heat Stressed Broiler [PDF]

, 2015
The present study aimed to explain the role of additives in alleviation of the negative effect of heat stress on differential leucocytes count, heterophil / lymphocytic ratio with especial studies on the microbial count of duodenum, jejunum, ileum and ...
Darwish, Madeha H.A., Abdel-Rahman, Mootaz A.M., EL Shoukary, Ramadan D.   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Microbial Quality and Mineral Content of Water Consumed in Ho Municipality of Volta Region, Ghana [PDF]

Journal of Food Quality and Hazards Control
Background: Water quality and safety are fundamental to human development and well-being. Therefore, the purpose of this study was to determine the bacteriological and mineral content of water in Ho, the capital city of the Volta Region of Ghana ...
G. Aboagye, P.G. Akpaloo, T.A. Avle
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

SOME STUDIES OF THE COLONY COUNT TECHNIQUE FOR SOIL BACTERIA

Journal of Applied Bacteriology, 1960
SUMMARY: A series of co‐operative experiments was conducted to compare the bacterial colony counts of soil obtained by workers in different laboratories, using soil extract agar and other media for the determinations. In the earlier experiments it was not possible to obtain a
Edgell, J. W., Cuthbert, W. A., Scarlett, C. A., Thomas, S. B., Westmacott, M. H., Bird, E. R., Harrison, J.   +6 more
openaire   +1 more source

Discovering Regression Rules with Ant Colony Optimization [PDF]

, 2015
The majority of Ant Colony Optimization (ACO) algorithms for data mining have dealt with classification or clustering problems. Regression remains an unexplored research area to the best of our knowledge.
Brookhouse, James, Otero, Fernando E.B., James Brookhouse, Fernando E.B. Otero   +3 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source