Land use changes associated with declining honey bee health across temperate North America
Urbanization and agricultural intensification continue to reshape landscapes, altering the habitat available to wildlife and threatening species of both economic and conservation concern.
Rodney T Richardson +9 more
doaj +1 more source
Climate change, forest conservation and science: A case study of New Zealand, 1860s-1920 [PDF]
To most of its European settlers, New Zealand was a land blessed by Providence. A temperate climate and year-round rainfall, easy availability of land and myriad work opportunities attracted many to the new colony.
Beattie, James John
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Quality of Life and Marital Adjustment after Cognitive Behavioural Therapy and Behavioural Marital Therapy in Couples with Anxiety Disorders [PDF]
Background: Anxiety disorders may affect nearly one in four persons and may cause significant impairment of interpersonal relationships including marital relationships. The effect of the disorder on the spouse and the impact of including the spouse in
Chirumamilla Kavitha +2 more
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
AN1'IGF,NIC CHARACTEWSATION OF Pasteurella multocida ISOLATES FROM RABBIT-I [PDF]
Three strains of Y. Multorida comprising of 2 rabbit strains (R9S and R,,S) and a bovine vaccine strain (P-52) were used for antigen preparations viz., heat inactivated crude.
S. Manoharan, V. Jayaprakasan
doaj
Sewage Pollution in Kapoho Tide Pools (Preliminary Study) [PDF]
UH
Thomas, Terence P.
core +1 more source
Chronic exposure to neonicotinoids increases neuronal vulnerability to mitochondrial dysfunction in the bumblebee (Bombus terrestris) [PDF]
This work was funded jointly by the Biotechnology and Biological Sciences Research Council, the Department for Environment, Food and Rural Affairs, the Natural Environment Research Council, the Scottish Government, and The Wellcome Trust, under the ...
Bollan, Karen A. +7 more
core +3 more sources
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
The SMAC mimetic LCL-161 selectively targets JAK2V617F mutant cells. [PDF]
Background:Evasion from programmed cell death is a hallmark of cancer and can be achieved in cancer cells by overexpression of inhibitor of apoptosis proteins (IAPs).
Craver, Brianna M +6 more
core

