Results 81 to 90 of about 2,736,319 (288)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Curcumin‐Encapsulated Poly(lactic‐co‐glycolic acid) Nanoparticles: A Comparison of Drug Release Kinetics from Particles Prepared via Electrospray and Nanoprecipitation

Macromolecular Materials and Engineering
Controlled drug release (CDR) is a significant field of research in medical sciences due to its numerous clinical advantages over traditional methods. Encapsulation of a drug in a polymeric matrix is common technique to achieve CDR.
Zahra Roshan, Vahid Haddadi‐Asl, Hanie Ahmadi, Majid Moussaei   +3 more
doaj   +1 more source

Color categories: Evidence for the cultural relativity hypothesis [PDF]

, 2005
The question of whether language affects our categorization of perceptual continua is of particular interest for the domain of color where constraints on categorization have been proposed both within the visual system and in the visual environment ...
Davies, Ian R.L., Davidoff, Jules B., Shapiro, Laura R., Davidoff, J, Davidoff, Jules, Roberson, D, Davies, IRL, Shapiro, LR, Davies, Ian R. L., Roberson, Debi   +9 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

A Perceptual Method to Assess Color in Interfaces

, 2017
This paper presents a method, which applies a Spatial Color Algorithm (SCA) on an interface to assess its colors and contrast. SCAs belong to a family of algorithms, which aim to enhance images mimicking some behaviors of the human visual system.
M.P. Lanaro, A. Rizzi, LANARO, MATTEO PAOLO, C. Bonanomi, B.R. Barricelli   +4 more
core   +2 more sources

Nanostructured Sulfonated Polystyrene/Modified Chitosan Composite Membranes for Direct Methanol Fuel Cells

Macromolecular Materials and Engineering
Sulfonated polystyrene (SPS)‐based proton exchange membranes were fabricated and modified by incorporating pristine chitosan nanoparticles (CS), sulfonated chitosan nanoparticles (SCS), and phosphotungstic acid–functionalized chitosan nanoparticles (PWCS)
Mahdi Tohidian, Mehdi Zolfi Zinab, Negar Hanaei   +2 more
doaj   +1 more source

Developing a New Method of Transformation for Obtaining XYZ Color Values from RGB Images for Agricultural Applications

Sensors
The extraction of device-independent color values from affordable and accessible digital images based on a standard color space system is crucially necessary for agricultural applications, where color information for plant monitoring or diagnostics is ...
Vahid Mohammadi, Keivan Ansari, Pierre Gouton, Houda Attig   +3 more
doaj   +1 more source

CCC: Color Classified Colorization

CoRR
Automatic colorization of gray images with objects of different colors and sizes is challenging due to inter- and intra-object color variation and the small area of the main objects due to extensive backgrounds. The learning process often favors dominant features, resulting in a biased model.
Mrityunjoy Gain, Avi Deb Raha, Rameswar Debnath   +2 more
openaire   +3 more sources

Color Differences on the Lunar Surface [PDF]

, 1968
Both a detailed literature survey and a new observational study were performed to determine and extend the knowledge of spectral reflectivity differences (color differences) on the lunar surface in the extended visible wavelength region.
McCord, Thomas Bard
core   +1 more source