Results 61 to 70 of about 1,592,768 (266)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Hyperspectral dataset of historical documents and mock-ups from 400 to 1700 nm (HYPERDOC)

open access: yesScientific Data
HYPERDOC is a hyperspectral imaging dataset of historical documents and mock-ups, designed to facilitate research in material identification in the cultural heritage domain.
Ana Belén López-Baldomero   +10 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Curcumin‐Encapsulated Poly(lactic‐co‐glycolic acid) Nanoparticles: A Comparison of Drug Release Kinetics from Particles Prepared via Electrospray and Nanoprecipitation

open access: yesMacromolecular Materials and Engineering
Controlled drug release (CDR) is a significant field of research in medical sciences due to its numerous clinical advantages over traditional methods. Encapsulation of a drug in a polymeric matrix is common technique to achieve CDR.
Zahra Roshan   +3 more
doaj   +1 more source

Developing a New Method of Transformation for Obtaining XYZ Color Values from RGB Images for Agricultural Applications

open access: yesSensors
The extraction of device-independent color values from affordable and accessible digital images based on a standard color space system is crucially necessary for agricultural applications, where color information for plant monitoring or diagnostics is ...
Vahid Mohammadi   +3 more
doaj   +1 more source

Color terms and color concepts [PDF]

open access: yesJournal of Experimental Child Psychology, 2006
In their lead articles, both Kowalski and Zimiles (2006) and O'Hanlon and Roberson (2006) declare a general relation between color term knowledge and the ability to conceptually represent color. Kowalski and Zimiles, in particular, argue for a priority for the conceptual representation in color term acquisition.
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Color Geometry – Or Color Grammar? [PDF]

open access: yes, 2019
This article discusses some difficulties of the theory of color propounded by Meinong in his Re-marks on the Color Solid and the Mixture Law of 1903. First, I argue that Meinong’s geometrical approach faces at least three sets of difficulties related to the following assumptions: colors pos-sess a “nature” that can be grasped through intuition; they ...
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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