Results 111 to 120 of about 5,306,719 (287)

A Constant Approximation for Colorful k-Center

open access: yesCoRR, 2019
14 pages, Published in ESA ...
Sayan Bandyapadhyay   +3 more
openaire   +4 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Blue-light-emitting color centers in high-quality hexagonal boron nitride

open access: yesPhysical review B, 2019
Light emitters in wide band gap semiconductors are of great fundamental interest and have potential as optically addressable qubits. Here we describe the discovery of a new color center in high-quality hexagonal boron nitride (h-BN) with a sharp emission
Brian Shevitski   +10 more
semanticscholar   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Laser-cut patterned, micrometer-thin diamond membranes with coherent color centers for open microcavities

open access: yesMaterials for Quantum Technology
Micrometer-scale thin diamond devices are key components for various quantum sensing and networking experiments, including the integration of color centers into optical microcavities.
Yanik Herrmann   +12 more
doaj   +1 more source

The Center Colorıng of a Graph

open access: yesJournal of Discrete Mathematical Sciences and Cryptography, 2015
AbstractFor a nontrivial connected graph G, center coloring is a kind of coloring that is to color the vertices of a graph G is such a way that if vertices have different distance from the center then they must receive different colors. Two adjacent vertices can receive the same color.
Yorgancioglu, Zeynep Ors   +2 more
openaire   +5 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

A Diamond Temperature Sensor Based on the Energy Level Shift of Nitrogen-Vacancy Color Centers

open access: yesNanomaterials, 2019
The nitrogen-vacancy (NV) color center in chemical vapor deposition (CVD) diamond has been widely investigated in quantum information and quantum biosensors due to its excellent photon emission stability and long spin coherence time.
Mingyang Yang   +10 more
semanticscholar   +1 more source

A p-centered coloring for the grid using O(p) colors

open access: yesDiscrete Mathematics
A $p$-centered coloring of a graph $G$, where $p$ is a positive integer, is a coloring of the vertices of $G$ in such a way that every connected subgraph of $G$ either contains a vertex with a unique color or contains more than $p$ different colors. We give an explicit construction of a $p$-centered coloring using $O(p)$ colors for the planar grid.
Mathew C. Francis, Drimit Pattanayak
openaire   +3 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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