Results 111 to 120 of about 19,331,121 (349)
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Optical Coronagraphic Spectroscopy of AU Mic: Evidence of Time Variable Colors?
, 2017 We present coronagraphic long slit spectra of AU Mic's debris disk taken with the STIS instrument aboard the Hubble Space Telescope (HST). Our spectra are the first spatially resolved, scattered light spectra of the system's disk, which we detect at ...
Debes, John H. +6 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Sniffer used as portable hydrogen leak detector [PDF]
, 1966 Sniffer type portable monitor detects hydrogen in air, oxygen, nitrogen, or helium. It indicates the presence of hydrogen in contact with activated palladium black by a change in color of a thermochromic paint, and indicates the quantity of hydrogen by a
Dayan, V. H., Rommel, M. A.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Basic perceptual changes that alter meaning and neural correlates of recognition memory
Frontiers in Human Neuroscience, 2015 It is difficult to pinpoint the border between perceptual and conceptual processing, despite their treatment as distinct entities in many studies of recognition memory.
Chuanji eGao +3 more
doaj +1 more source
, 2003 The purpose of this activity is to measure ozone concentrations at ground level. Students deploy a strip of paper that changes color in the presence of ozone.
The GLOBE Program, UCAR (University Corporation for Atmospheric Research)
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Anthocyanin contents and molecular changes in rose petals during the post-anthesis color transition
Ornamental Plant ResearchFlower color transitions during anthesis are taxonomically widespread; however, the mechanisms underlying post-anthesis color transition in roses are unclear.
Ying Kong +5 more
doaj +1 more source