Results 71 to 80 of about 679,153 (291)

Shape encoding consistency across colors in primate V4

Journal of Neurophysiology, 2012
Neurons in primate cortical area V4 are sensitive to the form and color of visual stimuli. To determine whether form selectivity remains consistent across colors, we studied the responses of single V4 neurons in awake monkeys to a set of two-dimensional shapes presented in two different colors.
Brittany N, Bushnell, Anitha, Pasupathy
openaire   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Fluctuations and the rapidity dependence of charged particles spectra in fixed centrality bins in p$A$ collisions

, 2016
We argue that large fluctuations in the saturation momentum are necessary to explain the ATLAS and ALICE data on pA collisions measured at the LHC. Using a form for the distribution of fluctuations motivated by theoretical studies of the non-linear ...
McLerran, Larry, Praszalowicz, Michal
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Consistency and Standardization of Color in Medical Imaging: a Consensus Report [PDF]

, 2014
This article summarizes the consensus reached at the Summit on Color in Medical Imaging held at the Food and Drug Administration (FDA) on May 8–9, 2013, co-sponsored by the FDA and ICC (International Color Consortium).
Badano, A, Boynton, P, Casertano, A, Cheng, W-C, Clunie, D, Flynn, MJ, Green, P, Heki, T, Hewitt, S, Homma, H, Kimpe, T, Krupinski, E, Masia, A, Matsui, T, Nagy, B, Nishibori, M, Penczek, J, Revie, C, Schopf, T, Sisson, C, Skrøvseth, S, Treanor, D, Yagi, Y, Yokoi, H   +23 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Physical Properties of Estrus Mucus in Relation to Conception Rates in Dairy Cattle

Journal of Animal Reproduction and Biotechnology, 2014
The study aimed to determine the physical characteristics of estrus mucus and conception rates in dairy cattle. Samples of estrus mucus from the cervix were collected from 108 dairy cattle during heat and were examined for color and consistency.
Hyun-Joo Lim, Jun-Kyu Son, Ho-Beak Yoon, Kwang-Soo Baek, Tae-il Kim, Yeon-Sub Jung, Eung-Gi Kwon   +6 more
doaj   +1 more source

An Examination of Recent Transformations to the BV(RI)_C Photometric System from the Perspective of Stellar Models for Old Stars

, 2010
Isochrones for ages > 4 Gyr and metallicities in the range -2.5 < [Fe/H] < +0.3 that take the diffusion of helium and recent advances in stellar physics into account are compared with observations in the Johnson-Cousins BV(RI)_C photometric system for ...
Bahcall, Bergbusch, Bergbusch, Bessell, Bessell, Boesgaard, Bohlin, Brasseur, Cacciari, Calamida, Caldwell, Carretta, Casagrande, Cassisi, Cayrel de Strobel, Christensen-Dalsgaard, Clem, Don A. VandenBerg, Dotter, Dotter, Edvardsson, Gratton, Kaluzny, Koch, Kučinskas, L. Casagrande, Magic, McCall, Meléndez, Meléndez, Michaud, Milone, Paulson, Peter B. Stetson, Pietrinferni, Ramírez, Reid, Rood, Sarajedini, Schlegel, Skrutskie, Stetson, Tautvaišiene, VandenBerg, VandenBerg, VandenBerg, VandenBerg, VandenBerg, VandenBerg, Weiss, Weiss, Yong   +51 more
core   +1 more source

The Essential Role of String-Derived Symmetries in Ensuring Proton-Stability and Light Neutrino Masses [PDF]

, 1996
The paper addresses the problem of suppressing naturally the unsafe d=4 as well as the color-triplet mediated and/or gravity-linked d=5 proton-decay operators, which generically arise in SUSY-unification.
Pati, Jogesh C.
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source