Results 61 to 70 of about 1,169,824 (282)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

A Physical Basis for Color Constancy [PDF]

, 2002
A fundamental problem in psychophysical experiments is that significant conclusions are hard to draw due to the complex experimental environment necessary to examine color constancy.
Theo Gevers, Rein van den Boomgaard, Boomgaard, R. van den, van den Boomgaard, R., Gevers, Th., Jan-Mark Geusebroek, Gevers, T., Arnold W M Smeulders, Smeulders, A.W.M., Geusebroek, J.M., Geusebroek, J.M. (Jan-Mark), Smeulders, A.W.M. (Arnold)   +11 more
core  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Color constancy using stage classification

, 2009
The aim of color constancy is to remove the effect of the color of the light source. Since color constancy is inherently an ill-posed problem, different assumptions have been proposed.
De Xu, Jan-Mark Geusebroek, Gijsenij, A., Gevers, T., van de Sande, K., Xu, D., Geusebroek, J.M., Theo Gevers, Lu, R., Arjan Gijsenij, Rui Lu, Koen van de Sande   +11 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Challenges to Color Constancy in a Contemporary Light [PDF]

Color constancy is a prime example of a perceptual constancy, giving stability to mental representations of objects in an unstable world. Yet color constancy is highly variable, depending on the illumination, the object and its context, and the viewer ...
Hurlbert A
core   +3 more sources

The effect of background and illumination on color identification of real, 3D objects

Frontiers in Psychology, 2013
For the surface reflectance of an object to be a useful cue to object identity, judgments of its color should remain stable across changes in the object's environment. In 2D scenes, there is general consensus that color judgments are much more stable
Sarah Ray Allred, Maria eOlkkonen
doaj   +1 more source

Color Constancy Using Single Colors [PDF]

, 2012
This work investigates if the von Kries adaptation can be generalized to deal with single colored patches. We investigate which colored patches can give statistically equivalent performance to a white patch for von Kries adaptation. The investigation is then extended to couples of colors, and the analysis of the characteristics of the colors forming ...
openaire   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source