Results 91 to 100 of about 430,144 (311)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Effect of Toothpaste with Blue Covarine on Color Stability and Demineralization after Bleaching Treatments

open access: yesCurrent Research in Dental Sciences
Objective: The aim of this study is to investigate the effect of toothpaste containing blue covarine after in-office and at-home bleaching treatments on color stability and demineralization of enamel.
Neslihan Çelik, Seyit Bilal Özdemir
doaj   +1 more source

Avaliação da microdureza e cor de cimentos resinosos inseridos em diferentes substância e PH [PDF]

open access: yes, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2014O objetivo deste estudo in vitro foi de avaliar a microdureza e a alteração da cor de quatro cimentos ...
Santos Neto, Cássio dos
core  

Enhancement of color stability in strawberry nectar during storage

open access: yes, 2021
Strawberry anthocyanins often undergo chemical degradation during storage, which leads to color fading and bioactivity loss. These changes are increased by ascorbic acid, which accelerates anthocyanin degradation.
Wafaa A. Amin   +2 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Effect of Acidic Media on Surface Topography and Color Stability of Two Different Glass Ceramics

open access: yes
Objective The aim of this study was to determine the effect of two acidic beverages (orange juice and H3PO4-containing fizzy drink) on the surface topography and color stability of two commonly used computer-aided design/computer-aided manufacturing (CAD/
Makkeyah, Fatma   +3 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Color Stability of New Composite Restorative Materials Under Accelerated Aging [PDF]

open access: yes, 1980
The color stability of seven microfilled and conventional composites under conditions of accelerated aging was evaluated by reflection spectrophotometry. During early aging the composites generally became darker, more chromatic, and more opaque.
J.M. Powers   +5 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Color Stability of a Pigmented Elastomer for Maxillofacial Appliances [PDF]

open access: yes, 1979
The color stability of a series of eleven maxillofacial pigments was determined after accelerated aging using reflection spectrophotometry. The results indicate that seven of the pigments demonstrated good to excellent color stability, while four of the ...
Yu, Robert   +7 more
core   +1 more source

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