Results 101 to 110 of about 136,487 (304)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The Genetic Basis of Melanism in Abert’s Squirrel (Sciurus aberti)
AnimalsMelanism is widespread in different taxa and has been hypothesized to provide adaptive benefits in certain environments. Melanism is typically caused by mutations in one of two regulatory genes: the Melanocortin 1 Receptor (MC1R) or the Agouti Signaling ...
Lake H. Barrett +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Seasonal change in defensive coloration in a shieldbug [Elektronisk resurs]
, 2011 Protective coloration such as aposematism and crypsis occurs in many insects but only a few species alter their defensive strategy during the same instar. We hypothesize the adult shield bug Graphosoma lineatum with an alternating black and non-melanised
Johansen, Aleksandra Irene,
core
Quantifying Abdominal Coloration of Worker Honey Bees [PDF]
The main drawback in using coloration to identify honey bee subspecies is the lack of knowledge regarding genetic background, subjectivity of coloration grading, and the effect of the environment.
Janez Prešern +3 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Theoretical Computer Science, 2004 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Udo Adamy +3 more
openaire +3 more sources
Arc-coloration et sommet-coloration orientées
, 2006 Dans ce mémoire, nous nous intéressons à trois notions de colorations de graphes orientés : la sommet-coloration orientée, l'arc-coloration orientée et l'étoile-coloration orientée acircuitique. La notion de sommet-coloration orientée a été introduite en
SOPENA, Eric, PINLOU, Alexandre
core
, 2014 The purpose of designing this cut and sewn knit garment was to explore coloration through specified knit structures with an electronic circular jacquard knitting machine. This jacquard machine is limited in its design capacity since it can only hold four
Foster, Karis
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source