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Cancers of the colon and rectum will affect 1 in 17 North Americans during their lifetime. The progress witnessed in the treatment of these cancers in recent years has been remarkable. Improvements have been realized in surgical technique, radiation therapy, and systemic therapies, particularly with the addition of oxaliplatin and irinotecan to the ...
Anne B, Ballinger, Clive, Anggiansah
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Colorectal cancer (CRC) is one of the leading causes of mortality and accounts for approximately 200000 deaths per year in Europe and the USA. Chemotherapy and radiotherapy have established roles in the treatment of colorectal cancer and can contribute to cure rate, prolongation of survival, reduction of local rates of recurrence and enhanced quality ...
Nicum, S, Midgley, R, Kerr, D
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The inflammatory process plays a significant role in the development of colon cancer (CRC). Intestinal cytokine networks are critical mediators of tissue homeostasis and inflammation but also impact carcinogenesis at all stages of the disease.
Jędrzej Borowczak +7 more
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Robotic-assisted Surgery and its Impact on Patient Outcomes: A Narrative Review [PDF]
Robotic-assisted surgery is an advanced surgical technique that combines the skill of a surgeon with the precision and capabilities of robotic systems. This approach has revolutionised the field of medicine by providing enhanced visualisation, improved ...
Simran Chauhan +2 more
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Background: South Africa (SA) has the highest incidence of colorectal cancer (CRC) in Sub-Saharan Africa (SSA). However, there is limited research on CRC recurrence and survival in SA.
Okechinyere J. Achilonu +10 more
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Objectives: It has been increasingly recognized that the progression of cancer is dependent not only on the tumor characteristics but also on the nutritious and inflammatory condition of the host.
Ryuichiro Sato +11 more
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KRAS-associated microRNAs in colorectal cancer
Colorectal cancer (CRC) is one of the leading causes of cancerrelated death worldwide. Despite progress in treatment of cancers, CRC with KRAS mutations are resistant towards anti-EGFR treatment.
Hamizah Ibrahim, Ya Chee Lim
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Deficient mismatch repair (dMMR)/microsatellite instability-high (MSIH) colorectal cancer is resistant to conventional chemotherapy but responds to immune checkpoint inhibition (ICI).
Alan Su, Rodrigo Pedraza, Hagen Kennecke
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With colon cancer being one of the deadliest and most common cancers, understanding the mechanisms behind colon cancer is crucial in improving therapies. One of the newest approaches in cancer research is the concept of proteogenomics. While genomic data
Soumyadev Sarkar
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Carcinoma Rectum with Prostate and Urinary Bladder Metastasis- A Rare Case Report [PDF]
Tumours of the colon and rectum are one of the most common malignancies worldwide. In India, its incidence is less compared to the developed countries however,recently it has increased from past few decades due to sedentary lifestyle and more ...
Rabbavijaya Sowjanya Lakshmi +3 more
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