Results 101 to 110 of about 764,224 (312)

Supplemental Figures from Combined Menin and EGFR Inhibitors Synergize to Suppress Colorectal Cancer via EGFR-Independent and Calcium-Mediated Repression of SKP2 Transcription

, 2023
Bryson W. Katona, Rebecca A. Glynn, Kayla E. Paulosky, Zijie Feng, Caroline I. Davis, Jian Ma, Corbett T. Berry, Katherine M. Szigety, Smita Matkar, Yuanyuan Liu, Haoren Wang, Wu Yuan, Xin He, Bruce D. Freedman, Donita C. Brady, Xianxin Hua   +15 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Women's Performance in Conferences and Their Publications: A Critical Analysis

Journal of Coloproctology
Introduction Gender inequality occurs in all spheres of society, which is no different in the medical field. Abstract presentations in congress are the vanguard of scientific knowledge, an integral part of topic discussion, and, ideally ...
Hugo Samartine Junior, Giovanna Bertazzola Gracitelli, Lucas Rosasco Mazzini, Lauro Igor Silva, Nicole Goldenberg Levy, José Luis Braga de Aquino, Elisa Teixeira Mendes   +6 more
doaj   +1 more source

Hereditary non-polyposis colorectal cancer (HNPCC) and its genetic basis

, 2023
zulqarnain bhalwal
openalex   +2 more sources

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Appendiceal Goblet Cell Carcinoma: Comparison of Classification and Staging Systems with Evaluation of the Prognostic Role of Immunohistochemistry Stains

Journal of Coloproctology
Background Goblet cell carcinoma (GCC) of the appendix is a unique lesion that exhibits features of both adenocarcinoma and neuroendocrine tumors.
Rachel Masia, Vincent Marcucci, Colton Moore, Xiu Sun, Arthur Topilow, Timothy Gelatt, Glenn Parker   +6 more
doaj   +1 more source

Supplementary Figure S8 from St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling

, 2023
Soumen K. Manna, Srujana Golla, Jaya Prakash Golla, Naoki Tanaka, Yan Cai, Shogo Takahashi, Kristopher W. Krausz, Tsutomu Matsubara, Ilia Korboukh, Frank J. Gonzalez   +9 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The Natural Flavonoid Fisetin Inhibits Cellular Proliferation of Hepatic, Colorectal, and Pancreatic Cancer Cells through Modulation of Multiple Signaling Pathways

, 2017
Mаhmoud Youns, Wael A. H. Hegazy
openalex   +2 more sources

Previously unrecognized genetic mutations in colorectal and breast cancers [PDF]

, 2006

openalex   +1 more source